Biological Activities of Algerian Bunium incrassatum (Boiss.) Batt. & Trab. Against Sodium Fluoride Toxicity in Rats

被引：0

作者：

Bouzid, Salha ^{[1
]}

Baali, Nacera ^{[2
]}

Rahmoune, Chaabane ^{[1
]}

Djebablah, Fatima ^{[3
]}

Henni, Nourelhouda ^{[3
]}

Baadache, Imene ^{[1
]}

Merrouche, Khaoula ^{[1
]}

Boutiouta, Chaima ^{[3
]}

Djidjeli, Khaoula ^{[3
]}

机构：

[1] Mentouri Bos Univ Constantine 1, Nat & Life Sci Fac, Plant Biol & Ecol Dept, BP 325 Route Ain El Bey, Constantine 25017, Algeria

[2] Mentouri Bros Univ Constantine 1, Nat & Life Sci Fac, Anim Biol Dept, Constantine, Algeria

[3] Mentouri Bros Univ Constantine 1, Nat & life Sci Fac, Mol & Cellular Biol & Biochem, Constantine, Algeria

来源：

FLUORIDE | 2024年 / 57卷 / 05期

关键词：

Buniumincrassatum; phenolic compounds; antioxidant and hepatoprotective activities; blood sugar; hemoglobin;

D O I：

暂无

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Objective Bunium incrassatum is one of the very important medicinal species grown in north of Algeria. In this work, the total phenolic, the flavonoid content and phytochemical screening of bioactive substance the speciesroots were investigated. Material and methodsIn order to evaluate the antioxidant and hepatoprotective activities of the species,the rats received sodium floride (NaF) concomitant with B. incrassatumroot extract in a dose of 300 mg/kg. Important parameters such as transaminases (AST and ALT), blood Sucre, total bilirubin and hemoglobin were conducted, also, antibacterial and antioxidant activitywere analyzed.Results The obtained results revealed remarkable antioxidant activities of B. incrassatumextract. Compared to the control group, the NaF-treated group showed significant increase in transaminases and bilirubin levels with concomitant decrease in blood sugar and hemoglobin levels. In the B. incrassatumco-treatmentwith NaF group, B. incrassatumrestored the changes observed by NaF treatment. ConclusionThese findings reveal that B. incrassatumsupplementation has a protective effect against NaF induced hepatotoxicity in rats caused by the pollutant sodium fluoride

引用

页数：9