Isolated Intracranial Hypertensions as Onset of Myelin Oligodendrocyte Glycoprotein Antibody Disease

被引：0

作者：

Papetti, Laura ^{[1
]}

Moltoni, Giulia ^{[2
,3
]}

Longo, Daniela ^{[2
]}

Monte, Gabriele ^{[1
]}

Dellepiane, Francesco ^{[2
]}

Pro, Stefano ^{[1
]}

Bracaglia, Giorgia ^{[4
]}

Ruscitto, Claudia ^{[1
]}

Verrotti, Alberto ^{[5
]}

Valeriani, Massimiliano ^{[1
,6
,7
]}

机构：

[1] Bambino Gesu Childrens Hosp IRCCS, Dev Neurol Unit, I-00165 Rome, Italy

[2] Bambino Gesu Childrens Hosp IRCCS, Funct & Intervent Neuroradiol Unit, I-00165 Rome, Italy

[3] Univ Roma La Sapienza, NESMOS Dept St Andrea Hosp, Neuroradiol Unit, Via Grottarossa,1035-1039, I-00189 Rome, Italy

[4] IRCCS, Bambino Gesu Childrens Hosp, Dept Diagnost & Lab Med Unit, Unit Allergy & Autoimmun, I-00165 Rome, Italy

[5] Univ Perugia, Dept Pediat, I-06123 Perugia, Italy

[6] Tor Vergata Univ, Hosp Rome, Syst Med Dept, I-00133 Rome, Italy

[7] Aalborg Univ, Ctr Sensory Motor Interact, DK-9220 Aalborg, Denmark

来源：

JOURNAL OF CLINICAL MEDICINE | 2024年 / 13卷 / 15期

关键词：

idiopathic intracranial hypertension; pseudotumor cerebri; secondary headache; MOGAD; MOG antibodies; CEREBROSPINAL-FLUID; METABOLISM; PRESSURE;

D O I：

10.3390/jcm13154468

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Myelin oligodendrocyte glycoprotein antibody disease (MOGAD) is characterized by multiple phenotypic conditions such as acute disseminated encephalomyelitis, optic neuritis, and myelitis. MOGAD's spectrum is expanding, with potential symptoms of increased intracranial pressure that are similar to idiopathic intracranial hypertension (IIH). We report a boy with new-onset continuous headache and a brain MRI at onset suggesting idiopathic intracranial hypertension (IIH). The patient showed resistance to treatment with acetazolamide and, after one month, developed optic neuritis in the left eye. Laboratory tests documented positive MOG antibodies (anti-MOG) in the serum. The final diagnosis was MOGAD, with the initial symptoms resembling IIH.

引用

页数：10

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