Risk of gastrointestinal bleeding in Asian patients receiving oral anticoagulants for stroke prevention in atrial fibrillation

被引：0

作者：

Diaz, Alejandro Bimbo ^{[1
]}

Chow, Jeremy ^{[2
]}

Hoo, Fan Kee ^{[3
]}

Keong, Gary Lee Chin ^{[4
]}

Venketasubramanian, Narayanaswamy ^{[5
]}

Rey, Nannette ^{[6
]}

Rogelio, Gregorio ^{[7
]}

Mehta, Radhika ^{[8
]}

机构：

[1] Univ Santo Tomas Hosp, Manila, Philippines

[2] Asian Heart & Vasc Ctr, Singapore, Singapore

[3] Univ Putra Malaysia, Serdang, Malaysia

[4] Thomson Hosp Kota Damansara, Petaling Jaya, Malaysia

[5] Raffles Hosp, Singapore, Singapore

[6] De La Salle Med & Hlth Sci Inst, Dasmarinas Cavite, Philippines

[7] St Lukes Med Ctr, Quezon City, Philippines

[8] Menarini Asia Pacific Pte Ltd, Singapore, Singapore

来源：

DRUGS IN CONTEXT | 2024年 / 13卷

关键词：

Asian patients; atrial fibrillation; edoxaban; gastrointestinal bleeding; non-vitamin K oral anticoagulant; Southeast Asia; stroke; WARFARIN; EDOXABAN; DABIGATRAN; OUTCOMES; METAANALYSIS;

D O I：

10.7573/dic.2024-5-5

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Non-vitamin K antagonist oral anticoagulants (NOACs) are increasingly used for stroke prevention in atrial fibrillation. At the Asia Pacific Advancing Patient care with EdoXaban 2023 meeting, experts shared insights on gastrointestinal bleeding with NOACs for stroke prevention in atrial fibrillation in Asian clinical practice, where NOACs have gained widespread acceptance due to their favourable profiles. Gastrointestinal bleeding risk varies amongst NOACs, emphasizing the importance of diligent patient assessment, dosage selection and vigilant monitoring. Edoxaban emerged as a viable option with a low gastrointestinal bleeding risk profile in Asian compared with non-Asian patients, supporting its continued clinical utilization for appropriate patients.

引用

页数：15

共 33 条

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