Chromosome segregation: Mps1 and Dam1 battle to bind a shared interaction site at the kinetochore

被引:1
作者
Lacefield, Soni [1 ]
机构
[1] Geisel Sch Med Dartmouth, Dept Biochem & Cell Biol, Hanover, NH 03755 USA
关键词
SPINDLE CHECKPOINT; KINASE; ATTACHMENT;
D O I
10.1016/j.cub.2024.04.070
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The attachment of kinetochores to spindle microtubules is highly regulated to ensure proper chromosome segregation. Three new studies identify an interaction hub at the kinetochore that integrates kinetochore attachment state with spindle checkpoint activity and kinetochore assembly.
引用
收藏
页码:R530 / R533
页数:4
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