Neurological complications related to cardiac surgery present physicians with challenges. These complications severely impact patients' outcomes, the quality of their lives, and affect the resources available at healthcare centers. The treatment of neurological complications requires a multidisciplinary approach, where evidenced-based interventions work to identify the patient profiles and risk factors. In addition, ongoing investigations on alternative treatment methods like cerebral oximetry and personalized risk stratification may likely improve management and outcomes of such high-risk patients. Based on the significance that neurological problems play after cardiac surgery, this paper intends to offer the practitioners and scientists vital insights to help them provide the most suitable healthcare to the affected patients and to guide future studies.