gwid: an R package and Shiny application for Genome-Wide analysis of IBD data

被引：0
|
作者：
Mahmoudiandehkordi, Soroush [1 ,2 ]
Maadooliat, Mehdi [1 ,2 ]
Schrodi, Steven J. [2 ,3 ]
机构：
[1] Marquette Univ, Dept Math & Stat Sci, Milwaukee, WI 53233 USA
[2] Univ Wisconsin Madison, Dept Med Genet, 425-g Henry Mall, Madison, WI 53706 USA
[3] Univ Wisconsin Madison, Computat & Informat Biol & Med, Madison, WI 53706 USA
来源：
BIOINFORMATICS ADVANCES | 2024年 / 4卷 / 01期
关键词：
IDENTITY; DESCENT; ASSOCIATION;
D O I：
10.1093/bioadv/vbae115
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Genome-wide identity by descent (gwid) is an R package developed for the analysis of identity-by-descent (IBD) data pertaining to dichotomous traits. This package offers a set of tools to assess differential IBD levels for the two states of a binary trait, yielding informative and meaningful results. Furthermore, it provides convenient functions to visualize the outcomes of these analyses, enhancing the interpretability and accessibility of the results. To assess the performance of the package, we conducted an evaluation using real genotype data derived from the SNPs to investigate rheumatoid arthritis susceptibility from the Marshfield Clinic Personalized Medicine Research Project.
引用
收藏
页数：5
相关论文
共 50 条
  • [31] A fast algorithm and a new R package for visualization of genome-wide summary statistics
    Paria, Soumya Subhra
    Rahman, Sarthok Rasique
    Adhikari, Kaustubh
    HUMAN HEREDITY, 2022, VOL. (SUPPL 1) : 26 - 27
  • [32] QTLRel: an R Package for Genome-wide Association Studies in which Relatedness is a Concern
    Riyan Cheng
    Mark Abney
    Abraham A Palmer
    Andrew D Skol
    BMC Genetics, 12
  • [33] QTLRel: an R Package for Genome-wide Association Studies in which Relatedness is a Concern
    Cheng, Riyan
    Abney, Mark
    Palmer, Abraham A.
    Skol, Andrew D.
    BMC GENETICS, 2011, 12
  • [34] Simultaneous analysis of genome-wide SNP data
    Hoggart, C. J.
    De Iorio, M.
    Whittaker, J. C.
    Balding, D. J.
    GENETIC EPIDEMIOLOGY, 2007, 31 (06) : 609 - 609
  • [35] GINKGO: A R SHINY APPLICATION FOR PHARMACOKINETIC DATA ANALYSIS.
    Zheng, N.
    Li, M.
    Zhang, L.
    Chen, X.
    Zuo, Z.
    Criste, R.
    Wang, B.
    Yan, X.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2022, 111 : S30 - S30
  • [36] A revision of the InfiniumPurify R package for genome-wide correction of tumor purity in Infinium DNA methylation array data
    Hoang, Phuc H.
    GENES & DISEASES, 2023, 10 (03) : 698 - 700
  • [37] Genome-wide analysis of fitness data and its application to improve metabolic models
    Vitkin, Edward
    Solomon, Oz
    Sultan, Sharon
    Yakhini, Zohar
    BMC BIOINFORMATICS, 2018, 19
  • [38] Genome-wide analysis of fitness data and its application to improve metabolic models
    Edward Vitkin
    Oz Solomon
    Sharon Sultan
    Zohar Yakhini
    BMC Bioinformatics, 19
  • [39] GenABEL: an R library for genome-wide association analysis
    Aulchenko, Yurii S.
    Ripke, Stephan
    Isaacs, Aaron
    Van Duijn, Cornelia M.
    BIOINFORMATICS, 2007, 23 (10) : 1294 - 1296
  • [40] tRigon: an R package and Shiny App for integrative (path-)omics data analysis
    David L. Hölscher
    Michael Goedertier
    Barbara M. Klinkhammer
    Patrick Droste
    Ivan G. Costa
    Peter Boor
    Roman D. Bülow
    BMC Bioinformatics, 25
12345