gwid: an R package and Shiny application for Genome-Wide analysis of IBD data

被引：0
|
作者：
Mahmoudiandehkordi, Soroush [1 ,2 ]
Maadooliat, Mehdi [1 ,2 ]
Schrodi, Steven J. [2 ,3 ]
机构：
[1] Marquette Univ, Dept Math & Stat Sci, Milwaukee, WI 53233 USA
[2] Univ Wisconsin Madison, Dept Med Genet, 425-g Henry Mall, Madison, WI 53706 USA
[3] Univ Wisconsin Madison, Computat & Informat Biol & Med, Madison, WI 53706 USA
来源：
BIOINFORMATICS ADVANCES | 2024年 / 4卷 / 01期
关键词：
IDENTITY; DESCENT; ASSOCIATION;
D O I：
10.1093/bioadv/vbae115
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Genome-wide identity by descent (gwid) is an R package developed for the analysis of identity-by-descent (IBD) data pertaining to dichotomous traits. This package offers a set of tools to assess differential IBD levels for the two states of a binary trait, yielding informative and meaningful results. Furthermore, it provides convenient functions to visualize the outcomes of these analyses, enhancing the interpretability and accessibility of the results. To assess the performance of the package, we conducted an evaluation using real genotype data derived from the SNPs to investigate rheumatoid arthritis susceptibility from the Marshfield Clinic Personalized Medicine Research Project.
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页数：5
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