Kidney transplantation from a systemic lupus erythematosus donor and 1-year follow-up: A case report

被引：0

作者：

Zhou, Dawei ^{[1
]}

Leung, Junto ^{[1
]}

Xiong, Yan ^{[1
]}

Ye, Shaojun ^{[1
]}

Zhou, Wei ^{[1
]}

Ye, Qifa ^{[1
,2
]}

Wang, Yanfeng ^{[1
]}

机构：

[1] Wuhan Univ, Natl Qual Control Ctr Donated Organ Procurement, Inst Hepatobiliary Dis,Hubei Engn Ctr Nat Polymer, Zhongnan Hosp,Transplant Ctr,Hubei Key Lab Med Tec, Wuhan, Hubei, Peoples R China

[2] Cent South Univ, Xiangya Hosp 3, Natl Hlth Minist Transplantat Med Engn & Technol, Res Ctr, Changsha 410013, Hunan, Peoples R China

来源：

TRANSPLANT IMMUNOLOGY | 2024年 / 85卷

基金：

中国国家自然科学基金;

关键词：

Kidney transplantation; Systemic lupus erythematosus; Donor; DEPOSITION; DONATION;

D O I：

10.1016/j.trim.2024.102077

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Systemic lupus erythematosus (SLE) is usually regarded as a relative contraindication for deceased kidney donation. The pathological variations because of the changes in the immune environment after kidney transplantation (KT) are unclear, and the recovery of renal function is poorly understood. We present a case of KT from a deceased donor with SLE who was followed-up for one year. Although SLE-related hemangioma developed during the perioperative period, it was cured after interventional treatment. A pre-planned biopsy was performed one year after KT, and it was found that most of the pathological changes and immunofluorescent markers of lupus had resolved. Renal function was stable, and urinary protein and occult blood levels reduced one year after KT.

引用

页数：5