Effect of gamma-irradiation on the characteristics and anti-inflammatory activity of Sargassum fulvellum water extracts

被引：0

作者：

Jo, Mi Jeong ^{[1
]}

Xu, Xiaotong ^{[2
]}

Lee, Ji-Eun ^{[2
]}

Byun, Eui-Baek ^{[3
]}

Kim, Kwangwook ^{[4
]}

Byun, Eui-Hong ^{[4
]}

Ahn, Dong Hyun ^{[2
]}

机构：

[1] Pukyong Natl Univ, Ind Univ Cooperat Fdn, Dept Microbiol, Busan 48513, South Korea

[2] Pukyong Natl Univ, Dept Food Sci & Technol, Busan 48513, South Korea

[3] Korea Atom Energy Res Inst, Adv Radiat Technol Inst, Jeongeup Si 56212, Jeonbuk Do, South Korea

[4] Kongju Natl Univ, Dept Food Sci & Technol, Yesan 32439, Chungcheongnam, South Korea

来源：

RADIATION PHYSICS AND CHEMISTRY | 2024年 / 224卷

基金：

新加坡国家研究基金会;

关键词：

Anti-inflammatory effect; Degradation; Sargassum fulvellum; Gamma; -irradiation; MOLECULAR-WEIGHT; SODIUM ALGINATE; NITRIC-OXIDE; DEGRADATION; CYTOKINES;

D O I：

10.1016/j.radphyschem.2024.112072

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

This study was carried out to determine the effect of moderate gamma (gamma)-irradiation (3-20 kGy) on the characteristics and anti-inflammatory activity of Sargassum fulvellum water extracts (SFWEs). The SFWEs were gamma-irradiated with 3, 7, 10, and 20 kGy absorbed doses, and their pH, color value, reducing sugar content, and viscosity were measured. The reducing sugar content showed a 1.89-fold increase at 20 kGy compared to that in the non-irradiated SFWE, whereas the viscosity decreased with an increase in the irradiation dose. gamma-irradiated SFWEs decreased nitric oxide production more significantly than non-irradiated SFWEs. Moreover, gamma-irradiated SFWEs had a substantial inhibitory effect on the pro-inflammatory cytokine (interleukin-6 and tumor necrosis factor-alpha) secretion. Therefore, gamma-irradiation not only degrades S. fulvellum polysaccharides but also enhances S. fulvellum anti-inflammatory activity.

引用

页数：5

共 38 条

[1]

김민지, 2015, [Korean Journal of Fisheries and Aquatic Sciences, 한국수산과학회지], V48, P888

[2] Chlorophyll breakdown by gamma irradiation in a model system containing linoleic acid [J].