Hybrid Bladder Tumor: Urothelial Carcinoma With Squamous Cell Differentiation, Urothelial Sarcomatoid Carcinoma, and Concurrent Primary Mucinous Adenocarcinoma With Metastasis to the Penis

被引:1
作者
Antonov, Petar [1 ]
Raycheva, Gabriela [2 ]
Ivanov, Georgi [3 ]
Ivanov, Atanas
Uchikov, Petar [4 ]
Popov, Veselin [2 ]
Tzigarovski, Georgi [1 ]
Timev, Alexandar [5 ]
Grudeva, Zhanet [2 ]
机构
[1] Med Univ Plovdiv, Dept Urol & Gen Med, Plovdiv, Bulgaria
[2] Med Univ Plovdiv, Dept Clin Oncol, Plovdiv, Bulgaria
[3] Med Univ Plovdiv, Dept Gen & Clin Pathol, Plovdiv, Bulgaria
[4] Med Univ Plovdiv, Dept Special Surg, Plovdiv, Bulgaria
[5] Med Univ Sofia, Dept Urol, Sofia, Bulgaria
关键词
local recurrence of bladder cancer; muscle-invasive bladder cancer; bladder adenocarcinoma; penile; metastasis; hybrid bladder tumor; RADICAL CYSTECTOMY; URINARY-BLADDER; CANCER; RECURRENCE; FEATURES;
D O I
10.7759/cureus.68894
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The most common histological variants of bladder cancer include urothelial, squamous, and adenocarcinoma. In high-grade, invasive urothelial carcinoma, divergent differentiation can be observed, including glandular, squamous, trophoblastic, and small-cell types. Urothelial sarcomatoid carcinoma is characteristic of advanced carcinomas and is considered a possible common end route for all epithelial carcinomas. Adenocarcinoma of the bladder refers exclusively to true glandular carcinomas. Hybrid tumors are extremely rare and consist of more than one tumor type within the total tumor mass. Penile metastases are extremely uncommon, and there are no reported cases of metastatic adenocarcinoma of the bladder in the literature.
引用
收藏
页数:6
相关论文
共 50 条
  • [21] Squamous differentiation in pT1 bladder urothelial carcinoma predicts poor response for intravesical chemotherapy
    Li, Gang
    Hu, Jieping
    Niu, Yuanjie
    ONCOTARGET, 2018, 9 (01) : 217 - 223
  • [22] Comparative Outcomes of Pure Squamous Cell Carcinoma and Urothelial Carcinoma With Squamous Differentiation in Patients Treated With Radical Cystectomy
    Ehdaie, Behfar
    Maschino, Alexandra
    Shariat, Shahrokh F.
    Rioja, Jorge
    Hamilton, Robert J.
    Lowrance, William T.
    Poon, Stephen A.
    Al-Ahmadie, Hikmat A.
    Herr, Harry W.
    JOURNAL OF UROLOGY, 2012, 187 (01) : 74 - 79
  • [23] Squamous differentiation in patients with superficial bladder urothelial carcinoma is associated with high risk of recurrence and poor survival
    Li, Gang
    Yu, Jianpeng
    Song, Hualin
    Zhu, Shimiao
    Sun, Libin
    Shang, Zhiqun
    Niu, Yuanjie
    BMC CANCER, 2017, 17
  • [24] Protein Profiling of Bladder Urothelial Cell Carcinoma
    Hu, Jinghai
    Ye, Fei
    Cui, Miao
    Lee, Peng
    Wei, Chengguo
    Hao, Yuanyuan
    Wang, Xiaoqing
    Wang, Yanbo
    Lu, Zhihua
    Galsky, Matthew
    McBride, Russell
    Wang, Li
    Wang, Dongwen
    Cordon-Cardo, Carlos
    Wang, Chunxi
    Zhang, David Y.
    PLOS ONE, 2016, 11 (09):
  • [25] Bladder tumor histo-seminar - case 5: Urothelial carcinoma with squamous differentiation (basal type)
    Allory, Yves
    ANNALES DE PATHOLOGIE, 2016, 36 (06) : 390 - 393
  • [26] Squamous and/or glandular differentiation in urothelial carcinoma: Prevalence and significance in transurethral resections of the bladder
    Billis A.
    Schenka A.A.
    Ramos C.C.O.
    Carneiro L.T.
    Araújo V.
    International Urology and Nephrology, 2001, 33 (4) : 631 - 633
  • [27] Urothelial Carcinoma With Squamous Differentiation Is Associated With High Tumor Stage and Pelvic Lymph-Node Metastasis
    Liu, Yunguang
    Bui, Marilyn M.
    Xu, Bo
    CANCER CONTROL, 2017, 24 (01) : 78 - 82
  • [28] Histogenesis of sarcomatoid urothelial carcinoma of the urinary bladder: evidence for a common clonal origin with divergent differentiation
    Sung, M-T
    Wang, M.
    MacLennan, G. T.
    Eble, J. N.
    Tan, P-H
    Lopez-Beltran, A.
    Montironi, R.
    Harris, J. J.
    Kuhar, M.
    Cheng, L.
    JOURNAL OF PATHOLOGY, 2007, 211 (04) : 420 - 430
  • [29] Immunohistochemical Differentiation of Plasmacytoid Urothelial Carcinoma From Secondary Carcinoma Involvement of the Bladder
    Borhan, Walaa M.
    Cimino-Mathews, Ashley M.
    Montgomery, Elizabeth A.
    Epstein, Jonathan I.
    AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2017, 41 (11) : 1570 - 1575
  • [30] The clonal relation of primary upper urinary tract urothelial carcinoma and paired urothelial carcinoma of the bladder
    van Doeveren, Thomas
    Nakauma-Gonzalez, Jose A.
    Mason, Andrew S.
    van Leenders, Geert J. L. H.
    Zuiverloon, Tahlita C. M.
    Zwarthoff, Ellen C.
    Meijssen, Isabelle C.
    van der Made, Angelique C.
    van Der Heijden, Antoine G.
    Hendricksen, Kees
    van Rhijn, Bas W. G.
    Voskuilen, Charlotte S.
    van Riet, Job
    Dinjens, Winand N. M.
    Dubbink, Hendrikus J.
    van de Werken, Harmen J. G.
    Boormans, Joost L.
    INTERNATIONAL JOURNAL OF CANCER, 2021, 148 (04) : 981 - 987