Hybrid Bladder Tumor: Urothelial Carcinoma With Squamous Cell Differentiation, Urothelial Sarcomatoid Carcinoma, and Concurrent Primary Mucinous Adenocarcinoma With Metastasis to the Penis

被引:1
|
作者
Antonov, Petar [1 ]
Raycheva, Gabriela [2 ]
Ivanov, Georgi [3 ]
Ivanov, Atanas
Uchikov, Petar [4 ]
Popov, Veselin [2 ]
Tzigarovski, Georgi [1 ]
Timev, Alexandar [5 ]
Grudeva, Zhanet [2 ]
机构
[1] Med Univ Plovdiv, Dept Urol & Gen Med, Plovdiv, Bulgaria
[2] Med Univ Plovdiv, Dept Clin Oncol, Plovdiv, Bulgaria
[3] Med Univ Plovdiv, Dept Gen & Clin Pathol, Plovdiv, Bulgaria
[4] Med Univ Plovdiv, Dept Special Surg, Plovdiv, Bulgaria
[5] Med Univ Sofia, Dept Urol, Sofia, Bulgaria
关键词
local recurrence of bladder cancer; muscle-invasive bladder cancer; bladder adenocarcinoma; penile; metastasis; hybrid bladder tumor; RADICAL CYSTECTOMY; URINARY-BLADDER; CANCER; RECURRENCE; FEATURES;
D O I
10.7759/cureus.68894
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The most common histological variants of bladder cancer include urothelial, squamous, and adenocarcinoma. In high-grade, invasive urothelial carcinoma, divergent differentiation can be observed, including glandular, squamous, trophoblastic, and small-cell types. Urothelial sarcomatoid carcinoma is characteristic of advanced carcinomas and is considered a possible common end route for all epithelial carcinomas. Adenocarcinoma of the bladder refers exclusively to true glandular carcinomas. Hybrid tumors are extremely rare and consist of more than one tumor type within the total tumor mass. Penile metastases are extremely uncommon, and there are no reported cases of metastatic adenocarcinoma of the bladder in the literature.
引用
收藏
页数:6
相关论文
共 50 条
  • [1] Sarcomatoid Urothelial Carcinoma of the Urinary Bladder With Chondrosarcomatous and Concurrent Divergent Squamous Cell Carcinoma Differentiation- A Rare Entity
    Pal, Atanu Kumar
    Srinivas, Bheemanathi Hanuman
    Kalra, Sidhartha
    Dorairajan, Lalgudi N.
    Kodakkattil, Sreerag Sreenivasan
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2022, 14 (12)
  • [2] Clinical Significance of Squamous Differentiation in Urothelial Carcinoma of the Bladder
    Minato, Akinori
    Noguchi, Hirotsugu
    Tomisaki, Ikko
    Fukuda, Atsushi
    Kubo, Tatsuhiko
    Nakayama, Toshiyuki
    Fujimoto, Naohiro
    CANCER CONTROL, 2018, 25 (01)
  • [3] Surgical management of bladder urothelial carcinoma with squamous differentiation
    Raman, Jay D.
    Jafri, Syed M.
    UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, 2015, 33 (10) : 429 - 433
  • [4] Molecular mechanisms of squamous differentiation in urothelial cell carcinoma: A paradigm for molecular subtyping of urothelial cell carcinoma of the bladder
    Adam, Rosalyn M.
    DeGraff, David J.
    UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, 2015, 33 (10) : 444 - 450
  • [5] Oncologic Outcomes of Squamous Cell Carcinoma Versus Urothelial Carcinoma With Squamous Differentiation After Radical Cystectomy for Bladder Carcinoma
    Laymon, Mahmoud
    Mosbah, Ahmed
    Hashem, Abdelwahab
    Mahmoud, Osama
    Harraz, Ahmed M.
    Elsawy, Amr A.
    Abol-Enein, Hassan
    CLINICAL GENITOURINARY CANCER, 2022, 20 (02) : 148 - 154
  • [6] Cutaneous metastasis of bladder urothelial carcinoma
    Hasan, Osamah
    Houlihan, Matthew
    Wymer, Kevin
    Hollowell, Courtney M. P.
    Kohler, Tobias S.
    UROLOGY CASE REPORTS, 2020, 28
  • [7] Urothelial Carcinoma Versus Squamous Cell Carcinoma of Bladder: Is Survival Different With Stage Adjustment?
    Scosyrev, Emil
    Yao, Jorge
    Messing, Edward
    UROLOGY, 2009, 73 (04) : 822 - 827
  • [8] Malignant Infiltration of the Penis From Urothelial Carcinoma of the Bladder
    Tong, Carmen
    Daskalakis, Nikolas
    Edwards, Daniel C.
    Cahn, David B.
    Belkoff, Laurence
    Geynisman, Daniel M.
    UROLOGY, 2017, 107 : 23 - 25
  • [9] Comprehensive Assessment of Immuno-oncology Biomarkers in Adenocarcinoma, Urothelial Carcinoma, and Squamous-cell Carcinoma of the Bladder
    Necchi, Andrea
    Madison, Russell
    Raggi, Daniele
    Jacob, Joseph M.
    Bratslavsky, Gennady
    Shapiro, Oleg
    Elvin, Julia A.
    Vergilio, Jo-Anne
    Killian, Jonathan K.
    Ngo, Nhu
    Ramkissoon, Shakti
    Severson, Eric
    Hemmerich, Amanda C.
    Huang, Richard
    Ali, Siraj M.
    Chung, Jon H.
    Reddy, Prasanth
    Miller, Vincent A.
    Schrock, Alexa B.
    Gay, Laurie M.
    Alexander, Brian M.
    Grivas, Petros
    Ross, Jeffrey S.
    EUROPEAN UROLOGY, 2020, 77 (04) : 548 - 556
  • [10] Tumor necrosis in magnetic resonance imaging predicts urothelial carcinoma with squamous differentiation in muscle-invasive bladder carcinoma
    Park, Jae Hyon
    Kim, Milim
    Yoon, Jongjin
    Park, Insun
    Jung, Dae Chul
    Kang, Byung-Chul
    Oh, Young Taik
    ABDOMINAL RADIOLOGY, 2024, 49 (12) : 4341 - 4351