Intergenerational effects of maternal childhood maltreatment on newborns' stress regulation: The role of maternal depressive symptoms

被引：0

作者：

San Martin-Gonzalez, Nerea ^{[1
,2
,3
]}

Moya-Higueras, Jorge ^{[2
,4
]}

Eixarch, Elisenda ^{[5
,6
,7
,8
]}

Castro-Quintas, Agueda ^{[1
,2
,3
]}

Marques-Feixa, Laia ^{[1
,2
,3
]}

Crispi, Fatima ^{[5
,6
,7
,8
]}

Daura-Corral, Maria ^{[1
]}

de la Fuente-tomas, Lorena ^{[9
]}

Monteserin-Garcia, Jose Luis ^{[1
,2
,3
]}

Garcia-Portilla, Maria Paz ^{[2
,10
,11
]}

Fananas, Lourdes ^{[1
,2
,3
]}

机构：

[1] Univ Barcelona, Fac Biol, Dept Evolutionary Biol Ecol & Environm Sci, Barcelona, Spain

[2] Carlos III Hlth Inst, Network Ctr Biomed Res Mental Hlth CIBER SAM, Madrid, Spain

[3] Univ Barcelona IBUB, Inst Biomed, Barcelona, Spain

[4] Univ Lleida, Fac Educ Psychol & Social Work, Dept Psychol Sociol & Social Work, Lleida, Spain

[5] Univ Barcelona, Hosp Clin, BCNatal Fetal Med Res Ctr, Barcelona, Spain

[6] Univ Barcelona, Hosp St Joan Deu, Barcelona, Spain

[7] Inst Hlth Carlos III, Network Ctr Biomed Res Rare Dis CIBER ER, Madrid, Spain

[8] Univ Barcelona, Inst Invest Biomed August Pi Sunyer IDIBAPS i, Barcelona, Spain

[9] Univ Oviedo, Dept Psychol, Oviedo, Spain

[10] Univ Oviedo, Dept Psychiat, Oviedo, Spain

[11] Inst Invest Sanitaria Principado Asturias ISPA, Oviedo, Spain

来源：

CHILD ABUSE & NEGLECT | 2024年 / 155卷

关键词：

Maternal childhood maltreatment; Intergenerational; Stress regulation; Behavior; Cortisol reactivity; POSTPARTUM BONDING QUESTIONNAIRE; EARLY ADVERSITY; TRANSMISSION; TRAUMA; EXPOSURE; ABUSE; ASSOCIATIONS; VALIDATION; DISORDERS; MODEL;

D O I：

10.1016/j.chiabu.2024.106968

中图分类号：

D669 [社会生活与社会问题]; C913 [社会生活与社会问题];

学科分类号：

1204 ;

摘要：

Background: Maternal childhood maltreatment (CM) has been repeatedly associated with negative offspring's emotional outcomes. The dysregulation of the Hypothalamic-Pituitary-Adrenal (HPA) axis has emerged as the main underlying physiological mechanism. Objective: To explore the association between maternal CM and newborns' physiological and neurobehavioral stress responses, considering the role of perinatal maternal depression and bonding. Participants and setting: 150 healthy women were followed throughout pregnancy. 79 mother- infant dyads were included in the final analyses. Maternal CM was evaluated using the Childhood Trauma Questionnaire and depressive symptoms by the Edinburgh Postnatal Depression Scale (EPDS) at each trimester. At 7 weeks postpartum, the EPDS and the Postpartum Bonding Questionnaire were administered. Newborns' behavioral responses were assessed using "States Organization" (SO) and "States Regulation" (SR) subdomains of the Neonatal Behavioral Assessment Scale (NBAS). Newborns' salivary samples were collected before and after the NBAS to study cortisol reactivity. Methods: A cross-lagged panel model was employed. Results: Infants born to mothers with higher CM presented more optimal scores on SO ((3 (0.635) = 0.216, p (001) and SR (ss (0.273) = 0.195, p = .006), and a higher cortisol reactivity after NBAS handling ((3(0.019) = 0.217, p = .009). Moreover, newborns of mothers with higher CM and postpartum depressive symptoms exhibited a poorer performance on SR (ss (0.156 = - 0.288,p p = .002). Analyses revealed non-significant relationships between mother-infant bonding, newborns' cortisol reactivity and SO. Conclusions: Newborns from mothers with greater CM present higher cortisol reactivity and more optimal behavioral responses, which may reflect a prenatal HPA axis sensitization. However, those exposed to maternal postnatal depressive symptoms present poorer stress recovery.

引用

页数：12

共 51 条

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