Cyclodextrin-Based Nanogels for Stabilization and Sensing of Curcumin

被引：1

作者：

Casulli, Maria Antonietta ^{[1
]}

Yan, Ruyu ^{[2
]}

Takeuchi, Satomi ^{[2
]}

Cesari, Andrea ^{[3
,4
]}

Mancin, Fabrizio ^{[4
]}

Hayashita, Takashi ^{[2
]}

Hashimoto, Takeshi ^{[2
]}

Taurino, Irene ^{[1
,5
]}

机构：

[1] Katholieke Univ Leuven KU Leuven, Dept Elect Engn ESAT, Micro & Nanosyst MNS, B-3001 Leuven, Belgium

[2] Sophia Univ, Fac Sci & Technol, Grad Sch Sci & Technol, Dept Materals & Life Sci, Chiyoda Ku, Tokyo 1028554, Japan

[3] Univ Pisa, Dept Chem & Ind Chem, I-56124 Pisa, Italy

[4] Univ Padua, Dept Chem Sci, I-35131 Padua, Italy

[5] Katholieke Univ Leuven KU Leuven, Dept Phys & Astron, Semicond Phys HF, B-3001 Leuven, Belgium

来源：

ACS APPLIED NANO MATERIALS | 2024年 / 7卷 / 17期

关键词：

Curcumin; Cyclodextrins; Nanogels; Electrochemistry; Fluorescence; Nuclear MagneticResonance; Multi-Sensing; Stability; BETA-CYCLODEXTRIN; ELECTROCHEMICAL DETECTION; MEDICINAL-PLANTS; DIETARY CURCUMIN; IN-VITRO; ANTICANCER; HYDROGELS; FLUORESCENCE; ANTIOXIDANT; COMPLEXES;

D O I：

10.1021/acsanm.4c02972

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Curcumin (CUR), a polyphenolic substance from turmeric, displays diverse medicinal properties. However, its instability poses challenges in detection. Cyclodextrin-based nanogels (CyDngs) offer a transformative solution, enhancing CUR's stability in aqueous solutions. Multisensing approaches involving fluorescence, electrochemistry, and NMR spectroscopy were employed, demonstrating CyDngs' pivotal role in CUR detection. Langmuir analysis revealed a binding constant of 1.4 x 10(4) M-1 for CyDngs, highlighting their effectiveness over native beta-CyDs. The study emphasized CyDngs' superiority in stabilizing CUR and enabling reliable and sensitive detection with very diverse methods.

引用

页码：20153 / 20162

页数：10

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