Gliomas in adults: Guidance on investigations, diagnosis, treatment and surveillance

被引:1
作者
Lerner, Anna [1 ]
Palmer, Kieran [1 ]
Campion, Tom [2 ]
Millner, Thomas [3 ,4 ]
Scott, Emily [1 ]
Lorimer, Cressida [5 ]
Paraskevopoulos, Dimitrios [1 ]
Mckenna, Grainne [1 ]
Marino, Silvia [3 ,4 ]
Lewis, Rachel [1 ]
Plowman, Nick [1 ]
机构
[1] Barts Hlth NHS Trust, London, England
[2] Barts Hlth NHS Trust, Imaging Dept, London, England
[3] Queen Mary Univ London, Blizard Inst, London, England
[4] Barts Hlth NHS Trust, London, England
[5] Univ Hosp Sussex NHS Fdn Trust, Worthing, England
关键词
Glioma; Presentation; Diagnosis; Management; Complications; PHASE-III TRIAL; VINCRISTINE CHEMOTHERAPY; RESPONSE ASSESSMENT; PLUS PROCARBAZINE; BRAIN-TUMORS; GLIOBLASTOMA; TEMOZOLOMIDE; RESECTION; OLIGODENDROGLIOMA; RADIOTHERAPY;
D O I
10.1016/j.clinme.2024.100240
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Primary brain tumours are rare but carry a significant morbidity and mortality burden. Malignant gliomas are the most common subtype and their incidence is increasing within our ageing population. The diagnosis and treatment of gliomas involves substantial interplay between multiple specialties, including general medical physicians, radiologists, pathologists, surgeons, oncologists and allied health professionals. At any point along this pathway, patients can present to acute medicine with complications of their cancer or anti-cancer therapy. Increasing the awareness of malignant gliomas among general physicians is paramount to delivering prompt radiological and histopathological diagnoses, facilitating access to earlier and individualised treatment options and allows for effective recognition and management of anticipated complications. This article discusses evidence-based real-world practice for malignant gliomas, encompassing patient presentation, diagnostic pathways, treatments and their complications, and prognosis to guide management outside of specialist centres.
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页数:9
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