MALT1 Inhibitors for Treating Cancer and Immunological Diseases

被引：0
|
作者：
Sabnis, Ram W. [1 ]
机构：
[1] Smith Gambrell & Russell LLP, Atlanta, GA 30309 USA
来源：
ACS MEDICINAL CHEMISTRY LETTERS | 2024年 / 15卷 / 09期
关键词：
D O I：
10.1021/acsmedchemlett.4c00390
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Provided herein are novel MALT1 inhibitors, pharmaceutical compositions, use of such compounds in treating cancer and immunological diseases and processes for preparing such compounds.
引用
收藏
页码：1419 / 1420
页数：2
相关论文
共 50 条
  • [31] Targeting B-cell lymphomas with inhibitors of the MALT1 paracaspase
    Haifinger, Stephan
    Lenz, Georg
    Thome, Margot
    CURRENT OPINION IN CHEMICAL BIOLOGY, 2014, 23 : 47 - 55
  • [32] The MALT1 switch in autoimmunity
    Maria Papatriantafyllou
    Nature Reviews Immunology, 2012, 12 (12) : 807 - 807
  • [33] Masking MALT1: the paracaspase's potential for cancer therapy
    Vucic, Domagoj
    Dixit, Vishva M.
    JOURNAL OF EXPERIMENTAL MEDICINE, 2009, 206 (11): : 2309 - 2312
  • [34] Effects of MALT1 Inhibitors on cutaneous T-cell lymphoma cells
    Mayo, J.
    Velatooru, L.
    Wang, X.
    Duvic, M.
    Ni, X.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2023, 143 (05) : S272 - S272
  • [35] Development of selective small molecule inhibitors of cellular MALT1 protease activity
    Oberg, Fredrik G.
    Karlstrom, Sofia
    Henderson, Ian
    Hewitt, Ellen
    Kallin, Anders
    Sedig, Susanne
    Lindberg, Jimmy
    Sohlenius-Sternbeck, Anna-Karin
    Bethell, Richard
    Albertella, Mark
    CANCER RESEARCH, 2016, 76
  • [36] Natural Product Inhibitors of the Arginine-Specific Protease Activity of MALT1
    Castro, A.
    Smith, E. A.
    Krumpe, Haugh L. R.
    O'Keefe, B. R.
    Staudt, L. M.
    McMahon, J. B.
    Gustafson, K. R.
    PLANTA MEDICA, 2013, 79 (10) : 845 - 845
  • [37] MALT1 Rearrangements in BAL Fluid
    Borie, Raphael
    Wislez, Marie
    Fleury-Feith, Jocelyne
    Delfau-Larue, Marie-Helene
    Cadranel, Jacques
    CHEST, 2012, 142 (01) : 262 - 262
  • [38] MALT1 in glioblastoma: the Flowers of Evil
    Maghe, Clement
    Jacobs, Kathryn A.
    Bidere, Nicolas
    Gavard, Julie
    M S-MEDECINE SCIENCES, 2020, 36 (05): : 452 - 454
  • [39] Malt1 deficient mice develop osteoporosis independent of osteoclast-intrinsic effects of Malt1 deficiency
    Monajemi, Mahdis
    Fisk, Shera
    Pang, Yvonne C. F.
    Leung, Jessica
    Menzies, Susan C.
    Ben-Othman, Rym
    Cai, Bing
    Kollmann, Tobias R.
    Rozmus, Jacob
    Sly, Laura M.
    JOURNAL OF LEUKOCYTE BIOLOGY, 2019, 106 (04) : 863 - 877
  • [40] MALT1 Inhibitors and Degraders: Strategies for NF-κB-Driven Malignancies
    Zhang, Ru-Yue
    Wang, Zi-Xuan
    Zhang, Meng-Yuan
    Wang, Yu-Fan
    Zhou, Si-Li
    Xu, Jia-Lu
    Lin, Wen-Xuan
    Ji, Tian-Rui
    Chen, Ya-Dong
    Lu, Tao
    Li, Nian-Guang
    Shi, Zhi-Hao
    JOURNAL OF MEDICINAL CHEMISTRY, 2025, 68 (05) : 5075 - 5096
12345