Progress in research on ultrasound radiomics for predicting the prognosis of breast cancer

Breast cancer is the most common malignant tumor and the leading cause of cancer-related deaths in women worldwide. Effective means of predicting the prognosis of breast cancer are very helpful in guiding treatment and improving patients' survival. Features extracted by radiomics reflect the genetic and molecular characteristics of a tumor and are related to its biological behavior and the patient's prognosis. Thus, radiomics provides a new approach to noninvasive assessment of breast cancer prognosis. Ultrasound is one of the commonest clinical means of examining breast cancer. In recent years, some results of research into ultrasound radiomics for diagnosing breast cancer, predicting lymph node status, treatment response, recurrence and survival times, and other aspects, have been published. In this article, we review the current research status and technical challenges of ultrasound radiomics for predicting breast cancer prognosis. We aim to provide a reference for radiomics researchers, promote the development of ultrasound radiomics, and advance its clinical application. Ultrasound radiomics is in the preliminary research stage to predict the prognosis of breast cancer. Multimodal prediction models that combine data from patients' clinical data, pathological results, gene expression, multiple images, and other data are the future research directions. High-quality studies can advance the clinical application of radiomics in the accurate diagnosis and treatment of breast cancer.1.2.3. image