Association between whole egg consumption and depression among older adults: Birjand Longitudinal Aging Study (BLAS)

BACKGROUND: Egg consumption may be associated with the risk of depression. OBJECTIVES: We aimed to assess this possible relationship in the context of the Birjand longitudinal aging study (BLAS). METHODS: In this cross-sectional study PHQ-9 was used to assess depression in a total of 1364 adults above 60 years of age, participating in the first stage of BLAS between September 2018 to April 2019. Socio-demographic information, anthropometric indices, and number of whole eggs consumed per week were assessed. Depression was assessed across the egg consumption groups: low (<= 1 eggs/week), moderate (>= 2 to <= 3 eggs/week), and high (>= 4 eggs/week), and the association was investigated using logistic regression. RESULTS: Mean egg intake in the studied population was 2.4 eggs/week. In the crude model and after adjustment for age and sex, moderate and high egg consumption were both associated with lower risk of depression in older adults (P <= 0.05). Adjustment for more confounding variables revealed that only moderate egg consumption protected against depression, while high egg consumers were still at risk of depression. CONCLUSION: Both moderate and high egg intake had reverse association with depression, and reduced the odds of depression among the elderly to approximately 30-40%. Future longitudinal studies could better confirm this association.