Objective: To compare double -density sign on non -contrast computed tomography scan of paranasal sinuses with fungal sinusitis on histopathology. Method: This prospective study was conducted at the Shifa International Hospital, Islamabad, Pakistan, from July 1, 2021, to June 30, 2023, and comprised patients of either gender aged 20-60 years who were set to undergo functional endoscopic sinus surgery. Demographic characteristics and non -contrast computed tomography scan findings were recorded preoperatively, while microbiological and histopathology results were recorded post -operatively. The microbiological finding was taken as the gold standard. Data was analysed using SPSS 23. Results: Of the 201 patients, 123(61.2%) were males and 78(38.8%) were females. The overall mean age was 41.62 +/- 8.52 years. The diagnostic accuracy of a double -density sign on computed tomography scan showed sensitivity 90%, specificity 90.8%, positive predictive value 84%, and negative predictive value 94.4%. Conclusion: A higher rate of sensitivity and specificity indicated that non -contrast computed tomography scan was an effective modality that could be used for the diagnosis of fungal sinusitis.
