Functions of immunologically active peptides and their roles in intestinal inflammation

被引:0
|
作者
Wang, Litong [1 ]
Li, Yi [1 ]
Huang, Kunlun [1 ,2 ]
Wang, Qin [3 ]
He, Xiaoyun [1 ,2 ]
机构
[1] China Agr Univ, Coll Food Sci & Nutr Engn, Key Lab Precis Nutr & Food Qual, Key Lab Funct Dairy,Minist Educ, Beijing 100083, Peoples R China
[2] Minist Agr & Rural Affairs PR China, Key Lab Safety Assessment Genet Modified Organism, Beijing, Peoples R China
[3] China Agr Univ, State Key Lab Anim Biotech Breeding, Coll Anim Sci & Technol,Minist Agr & Rural Affairs, Natl Engn Lab Anim Breeding,Lab Anim Genet Breedin, Beijing 100193, Peoples R China
来源
FOOD FRONTIERS | 2025年 / 6卷 / 01期
基金
中国国家自然科学基金;
关键词
disease applications; immunologically active peptides; mechanism of action; structure; PERITONEAL-MACROPHAGE FUNCTIONS; NEUROPEPTIDE Y1 RECEPTOR; GENOME-WIDE ASSOCIATION; ANTIMICROBIAL PEPTIDES; CROHNS-DISEASE; PROTEIN HYDROLYSATE; SUSCEPTIBILITY LOCI; IN-VITRO; T-CELLS; IDENTIFICATION;
D O I
10.1002/fft2.441
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Immunologically active peptides are a class of peptides with immune functions such as enhancing body immunity, regulating cell growth and differentiation, migration, chemotaxis, neurotransmission, and inducing apoptosis of tumor cells. They have many features, such as small molecular weight, strong stability, high biological activity, easy to adjust the structure accurately, and easy to synthesize. Exploring the mechanism of action of immunologically active peptides can help the modification and development of immunologically active peptides. In this article, the functional properties of immunologically active peptides are described from the perspectives of structural classification of immunologically active peptides and regulatory mechanisms. The relationship between structure and function and the application of different mechanisms in diseases are reviewed, focusing on the role in intestinal inflammation. This article reviews the relationship between structure and function, as well as the application of different mechanisms in diseases, with a focus on their role in intestinal inflammation. image
引用
收藏
页码:124 / 141
页数:18
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