Regulation and Therapeutic Application of Long non-Coding RNA in Tumor Angiogenesis

被引:3
作者
Zhang, Shuo [1 ,2 ,3 ]
Xia, Yunxiu [1 ,2 ,3 ]
Chen, Weiwei [1 ]
Dong, Hongliang [1 ]
Cui, Bingjie [1 ]
Liu, Cuilan [1 ]
Liu, Zhiqiang [1 ,2 ]
Wang, Fei [1 ,4 ,5 ]
Du, Jing [1 ,2 ]
机构
[1] Binzhou Med Univ Hosp, Med Res Ctr, Binzhou, Peoples R China
[2] Binzhou Med Univ Hosp, Dept Gynecol, Binzhou, Peoples R China
[3] Binzhou Med Univ, Binzhou Med Univ Hosp, Sch Clin Med 1, Binzhou, Peoples R China
[4] Shandong Univ, Med Integrat & Practice Ctr, Jinan, Peoples R China
[5] Shandong Univ, Qilu Hosp, Jinan 250100, Peoples R China
基金
中国博士后科学基金; 中国国家自然科学基金;
关键词
angiogenesis; lncRNA; cancer; multidimensional modification; mechanism; therapeutic application; PROMOTES CELL-PROLIFERATION; ENDOTHELIAL-CELLS; IN-VITRO; CANCER; METASTASIS; MALAT1; DELIVERY; EXPRESSION; EXOSOMES; EPIGENETICS;
D O I
10.1177/15330338241273239
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Tumor growth and metastasis rely on angiogenesis. In recent years, long non-coding RNAs have been shown to play an important role in regulating tumor angiogenesis. Here, we review the multidimensional modes and relevant molecular mechanisms of long non-coding RNAs in regulating tumor angiogenesis. In addition, we summarize new strategies for tumor anti-angiogenesis therapies by targeting long non-coding RNAs. The aim of this study is to provide new diagnostic targets and treatment strategies for anti-angiogenic tumor therapy.
引用
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页数:16
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