Successful Treatment of Warm Autoimmune Hemolytic Anemia with a Positive Donath-Landsteiner Test Using Rituximab

被引：1
作者：
Hiranuma, Naoko [1 ]
Koba, Yusuke [1 ]
Kawata, Takahito [1 ,2 ]
Tamekane, Akira [1 ]
Watanabe, Mitsumasa [1 ]
机构：
[1] Hyogo Prefectural Amagasaki Gen Med Ctr, Dept Hematol, Amagasaki, Japan
[2] Kyoto Univ, Grad Sch Med, Dept Hematol & Oncol, Kyoto, Japan
来源：
INTERNAL MEDICINE | 2024年 / 63卷 / 15期
关键词：
autoimmune hemolytic anemia; blood transfusion; Donath-Landsteiner antibody test; paroxysmal cold hemoglobinuria; rituximab;
D O I：
10.2169/internalmedicine.2088-23
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Paroxysmal cold hemoglobinuria (PCH) is a rare disease in adults, and its concurrent presentation with warm-type autoimmune hemolytic anemia (AIHA) has not yet been reported. We encountered a 19-year-old woman with AIHA and a positive Donath-Landsteiner test result identified by a hemolytic attack during blood transfusion. She also showed positive results for the direct Coombs and Donath-Landsteiner antibody tests. After treatment with prednisolone followed by rituximab, the AIHA improved, and the DonathLandsteiner antibody test result turned negative. Clinicians should be aware that patients may present with concurrent warm-type AIHA and PCH and consider rituximab for its treatment.
引用
收藏
页码：2173 / 2176
页数：4
相关论文
共 50 条
  • [31] Severe refractory autoimmune hemolytic anemia with both warm and cold autoantibodies that responded completely to a single cycle of rituximab: A case report
    Gupta S.
    Szerszen A.
    Nakhl F.
    Varma S.
    Gottesman A.
    Forte F.
    Dhar M.
    Journal of Medical Case Reports, 5 (1)
  • [32] Healthcare resource utilization of patients with warm autoimmune hemolytic anemia initiating first line therapy of oral corticosteroids with or without rituximab
    Irina Murakhovskaya
    Concetta Crivera
    Ann Leon
    Evo Alemao
    Vamshi Ruthwik Anupindi
    Mitch DeKoven
    Victoria Divino
    Iris Lin
    Cathye Shu
    Tarek Ebrahim
    Annals of Hematology, 2024, 103 : 1139 - 1147
  • [33] Healthcare resource utilization of patients with warm autoimmune hemolytic anemia initiating first line therapy of oral corticosteroids with or without rituximab
    Murakhovskaya, Irina
    Crivera, Concetta
    Leon, Ann
    Alemao, Evo
    Anupindi, Vamshi Ruthwik
    Dekoven, Mitch
    Divino, Victoria
    Lin, Iris
    Shu, Cathye
    Ebrahim, Tarek
    ANNALS OF HEMATOLOGY, 2024, 103 (04) : 1139 - 1147
  • [34] Molecular typing of Kell, Kidd, and Duffy antigens in direct antiglobulin test-positive autoimmune hemolytic anemia patients
    Sonker, Atul
    Dubey, Anju
    Mohan, Yatendra
    ASIAN JOURNAL OF TRANSFUSION SCIENCE, 2024, 18 (01) : 56 - 61
  • [35] Clinical Features and Treatment Outcomes of Warm Autoimmune Hemolytic Anemia: A Retrospective Analysis of 60 Turkish Patients
    Yilmaz, Ferguen
    Kiper, Demet
    Koc, Meltem
    Karsli, Tugce
    Kilinc, Merve
    Gediz, Fusun
    Toptas, Tayfur
    Payzin, Bahriye
    INDIAN JOURNAL OF HEMATOLOGY AND BLOOD TRANSFUSION, 2019, 35 (03) : 523 - 530
  • [36] Warm Autoimmune Hemolytic Anemia with a Direct Antiglobulin Test Positive for C3 and Negative for IgG: A Case Study and Analytical Literature Review of Incidence and Severity
    Palla, Amruth R.
    Khimani, Farhad
    Craig, Michael D.
    CLINICAL MEDICINE INSIGHTS-CASE REPORTS, 2013, 6 : 57 - 60
  • [37] Successful treatment of multiple intracerebral aspergillosis with voriconazole alone in an Egyptian diabetic patient with autoimmune hemolytic anemia
    Hamdy Ibrahim
    Safwat Abdel Maksod
    Magdy Khorshed
    Hanan Rady
    Ahmed Alsisi
    Adel Mohamed
    Nasser Fouad
    Ayman Hamed
    Mohamed Hosny
    Alaaa Al Amir
    The Egyptian Journal of Internal Medicine, 35
  • [38] Severe refractory autoimmune hemolytic anemia with five-year complete hematologic response to third course of treatment with rituximab: A case report
    Abadie K.
    Hege K.M.
    Journal of Medical Case Reports, 8 (1)
  • [39] Successful treatment of multiple intracerebral aspergillosis with voriconazole alone in an Egyptian diabetic patient with autoimmune hemolytic anemia
    Ibrahim, Hamdy
    Maksod, Safwat Abdel
    Khorshed, Magdy
    Rady, Hanan
    Alsisi, Ahmed
    Mohamed, Adel
    Fouad, Nasser
    Hamed, Ayman
    Hosny, Mohamed
    Al Amir, Alaaa
    EGYPTIAN JOURNAL OF INTERNAL MEDICINE, 2023, 35 (01)
  • [40] Fostamatinib for the treatment of warm antibody autoimmune hemolytic anemia: Phase 2, multicenter, open-label study
    Kuter, David J.
    Rogers, Kerry A.
    Boxer, Michael A.
    Choi, Michael
    Agajanian, Richy
    Arnold, Donald
    Broome, Catherine M.
    Field, Joshua J.
    Murakhovskaya, Irina
    Numerof, Robert
    Tong, Sandra
    AMERICAN JOURNAL OF HEMATOLOGY, 2022, 97 (06) : 691 - 699
12345