PyBox-La(OTf)3-Catalyzed Enantioselective Diels-Alder Cycloadditions of 2-Alkenoylpyridines with Cyclopentadiene

被引：1

作者：

Wei, Hao ^{[1
]}

Zhang, Yujie ^{[1
]}

Jin, Sanlin ^{[1
]}

Yu, Ying ^{[2
]}

Chen, Ning ^{[1
]}

Xu, Jiaxi ^{[1
]}

Yang, Zhanhui ^{[1
]}

机构：

[1] Beijing Univ Chem Technol, Coll Chem, Dept Organ Chem, Beijing 100029, Peoples R China

[2] China United Test & Certificat Co Ltd, Beijing 100088, Peoples R China

来源：

MOLECULES | 2024年 / 29卷 / 13期

关键词：

PyBox; rare earth; asymmetric catalysis; Diels-Alder cycloaddition; norbornene derivatives; HIGHLY EFFICIENT; DNA; METALLOENZYMES; CATALYST; CREATION; SITE;

D O I：

10.3390/molecules29132978

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The PyBox-La(OTf)(3)-catalyzed enantioselective Diels-Alder cycloaddition of 2-alk-2-enoylpyridines with cyclopentadiene is realized, producing enantiopure disubstituted norbornenes, which possess four contiguous stereocenters and are biologically relevant structures in up to 92:8 dr and 99:1 er.

引用

页数：16

共 30 条

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