Overt Hepatic Encephalopathy: More Than Meets the Eye

被引：1
|
作者：
Erminelli, Davide [1 ]
Mangini, Chiara [1 ]
Zarantonello, Lisa [1 ]
Angeli, Paolo [1 ]
Montagnese, Sara [1 ,2 ]
机构：
[1] Univ Padua, Dept Med, Padua, Italy
[2] Univ Surrey, Fac Hlth & Med Sci, Chronobiol Sect, Guildford, England
来源：
AMERICAN JOURNAL OF GASTROENTEROLOGY | 2024年 / 119卷 / 09期
基金：
欧盟地平线“2020”;
关键词：
cirrhosis; hepatic encephalopathy; neuropsychology; electroencephalography; ammonia;
D O I：
10.14309/ajg.0000000000002795
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
INTRODUCTION: We aimed to assess the reliability of a qualitative approach to overt hepatic encephalopathy (OHE) diagnosis compared with the semiquantitative, and recommended one. METHODS: The above 2 methods were compared in 411 outpatients (71% males, 60 +/- 10 years, model for end-stage liver disease 13.5 +/- 5.0). RESULTS: Of the 73 patients with OHE on quantitative assessment, 19 (26%) were missed on qualitative assessment, with no difference in the likelihood of the physician missing grades II or III. Sixty-eight (20%) of the 270 patients with no OHE on quantitative assessment were wrongly qualified as having OHE. DISCUSSION: Qualitative clinical evaluation of OHE is not reliable, and recommendations should be followed.
引用
收藏
页码：1930 / 1934
页数：5
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