Neonatal point-of-care testing

被引:3
作者
Naghdi, Tina [1 ,2 ]
Sharifi, Amir Reza [1 ]
Tabatabaee, Raziyeh Sadat [1 ]
Azizi, Elmira [1 ]
Kiani, Mohammad Ali [1 ]
Golmohammadi, Hamed [1 ,2 ]
机构
[1] Chem & Chem Engn Res Ctr Iran, Nanosensor Bioplatforms Lab, Tehran 14335186, Iran
[2] Univ Freiburg, Dept Microsyst Engn, IMTEK, D-79110 Freiburg, Germany
关键词
Neonate disease; Neonatal health monitoring; Point of care; Diagnostic device; Sensor; SYRUP-URINE-DISEASE; LACTATE-DEHYDROGENASE; PERINATAL ASPHYXIA; RAPID DIAGNOSIS; DIAZO-REACTION; AMINO-ACIDS; BILIRUBIN; PHENYLKETONURIA; QUANTIFICATION; GALACTOSEMIA;
D O I
10.1016/j.trac.2024.117732
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
More than 6000 infant deaths every day in just the first month of life is a severe alarm for healthcare systems on the eve of Healthcare 5.0. By providing timely, reliable, yet affordable and easy-to-use on-site diagnostic tests, and enabling neonatal health monitoring at home even in rural or remote areas, neonatal point-of-care testing (NPOCT) can be vital in reducing neonatal morbidity and mortality rates. In this review, considering the necessity of further development of NPOCTs, a comprehensive overview on the different types of (bio)sensors developed for POC monitoring of neonatal health is presented. Here, alongside reviewing the developed NPOCTs, the relevant neonatal disease is briefly introduced. Furthermore, to determine how far they are from ideal diagnostic devices, the developed NPOCTs are scored according to WHO's REASSURED criteria by highlighting their met/unmet characterizations. Finally, future prospects and views on the remaining challenges facing the further development of NPOCTs are provided.
引用
收藏
页数:20
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