Mu Opioid Receptor Knockout in Rostral Ventromedial Medulla Neurons Versus Presynaptic Terminals Has Divergent Effects on Acute Pain Phenotypes in Mice

被引:0
|
作者
Moffa, Jamie [1 ]
Kalyanaraman, Vani [1 ]
Heitmeier, Monique [1 ]
Grossman, Heather [1 ]
Copits, Bryan [1 ]
机构
[1] Washington Univ, St Louis, MO 63110 USA
来源
JOURNAL OF PAIN | 2024年 / 25卷 / 04期
关键词
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
引用
收藏
页码:17 / 17
页数:1
相关论文
共 10 条
  • [1] Rostral ventromedial medulla neurons that project to the spinal cord express multiple opioid receptor phenotypes
    Marinelli, S
    Vaughan, CW
    Schnell, SA
    Wessendorf, MW
    Christie, MJ
    JOURNAL OF NEUROSCIENCE, 2002, 22 (24): : 10847 - 10855
  • [2] Opioid receptor modulation of GABAergic and serotonergic spinally projecting neurons of the rostral ventromedial medulla in mice
    Pedersen, Nigel P.
    Vaughan, Christopher W.
    Christie, MacDonald J.
    JOURNAL OF NEUROPHYSIOLOGY, 2011, 106 (02) : 731 - 740
  • [3] Effect of Exercise on mu-Opioid Receptor Expression in the Rostral Ventromedial Medulla in Neuropathic Pain Rat Model
    Kim, Young-Jin
    Byun, Jeong-Hyun
    Choi, In-Sung
    ANNALS OF REHABILITATION MEDICINE-ARM, 2015, 39 (03): : 331 - 339
  • [4] Mu opioid receptor expressing neurons in the rostral ventromedial medulla are the source of mechanical hypersensitivity induced by repeated restraint stress
    Imbe, Hiroki
    Ihara, Hayato
    BRAIN RESEARCH, 2023, 1815
  • [5] Descending facilitation from rostral ventromedial medulla mu opioid receptor-expressing neurons is necessary for maintenance of sensory and affective dimensions of chronic neuropathic pain
    Dogrul, Bekir Nihat
    Kopruszinski, Caroline Machado
    Eslami, Mahdi Dolatyari
    Watanabe, Moe
    Luo, Shizhen
    de Souza, Luiz Henrique Moreira
    Vizin, Robson Lilo
    Yue, Xu
    Palmiter, Richard D.
    Navratilova, Edita
    Porreca, Frank
    PAIN, 2025, 166 (01) : 153 - 159
  • [6] Selective ablation of mu-opioid receptor expressing neurons in the rostral ventromedial medulla attenuates stress-induced mechanical hypersensitivity
    Reynolds, Jacques
    Bilsky, Edward J.
    Meng, Ian D.
    LIFE SCIENCES, 2011, 89 (9-10) : 313 - 319
  • [7] Evaluation of side effects through selective ablation of the mu opioid receptor expressing descending nociceptive facilitatory neurons in the rostral ventromedial medulla with dermorphin-saporin
    Cao, Fei
    Chen, Sha-Sha
    Yan, Xiao-Feng
    Xiao, Xing-Peng
    Liu, Xi-Jiang
    Yang, Shao-Bing
    Xu, Ai-Jun
    Gao, Feng
    Yang, Hui
    Chen, Zhi-Jun
    Tian, Yu-Ke
    NEUROTOXICOLOGY, 2009, 30 (06) : 1096 - 1106
  • [8] Regular physical activity reduces the percentage of spinally projecting neurons that express mu-opioid receptors from the rostral ventromedial medulla in mice
    Sluka, Kathleen A.
    Danielson, Jessica
    Rasmussen, Lynn
    Kolker, Sandra J.
    PAIN REPORTS, 2020, 5 (06)
  • [9] Mechanisms responsible for the enhanced antinociceptive effects of μ-opioid receptor agonists in the rostral ventromedial medulla of male rats with persistent inflammatory pain
    Sykes, Kenneth T.
    White, Stephanie R.
    Hurley, Robert W.
    Mizoguchi, Hirokazu
    Tseng, Leon F.
    Hammond, Donna L.
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2007, 322 (02): : 813 - 821
  • [10] Effects of acute "binge" cocaine on preprodynorphin, preproenkephalin, proopiomelanocortin, and corticotropin-releasing hormone receptor mRNA levels in the striatum and hypothalamic-pituitary-adrenal axis of mu-opioid receptor knockout mice
    Zhou, Y
    Spangler, R
    Schlussman, SD
    Yuferov, VP
    Sora, I
    Ho, A
    Uhl, GR
    Kreek, MJ
    SYNAPSE, 2002, 45 (04) : 220 - 229