Rectal Cancer, Version 3.2024 Featured Updates to the NCCN Guidelines

被引:0
作者
Benson III, Al B. [1 ]
Venook, Alan P. [2 ]
Adam, Mohamed [2 ]
Chang, George [3 ]
Chen, Yi-Jen [4 ]
Ciombor, Kristen K. [5 ]
Cohen, Stacey A. [6 ]
Cooper, Harry S. [7 ]
Deming, Dustin [8 ]
Garrido-Laguna, Ignacio [9 ]
Grem, Jean L. [10 ]
Haste, Paul [11 ]
Hecht, J. Randolph [12 ]
Hoffe, Sarah [13 ]
Hunt, Steven [14 ,15 ]
Hussan, Hisham [16 ]
Johung, Kimberly L. [17 ]
Joseph, Nora [18 ]
Kirilcuk, Natalie [19 ]
Krishnamurthi, Smitha [20 ,21 ]
Malla, Midhun [22 ]
Maratt, Jennifer K. [11 ]
Messersmith, Wells A. [23 ]
Meyerhardt, Jeffrey [24 ]
Miller, Eric D. [25 ,26 ]
Mulcahy, Mary F. [1 ]
Nurkin, Steven [27 ]
Parikh, Aparna [28 ]
Patel, Hitendra [29 ]
Pedersen, Katrina [14 ,15 ]
Saltz, Leonard [30 ]
Schneider, Charles [31 ]
Shibata, David [32 ]
Shogan, Benjamin [33 ]
Skibber, John M. [3 ]
Sofocleous, Constantinos T. [30 ]
Tavakkoli, Anna [34 ]
Willett, Christopher G. [35 ]
Wu, Christina [36 ]
Jones, Frankie [37 ]
Gurski, Lisa [37 ]
机构
[1] Northwestern Univ, Robert H Lurie Comprehens Canc Ctr, Evanston, IL 60208 USA
[2] UCSF Helen Diller Family Comprehens Canc Ctr, San Francisco, CA USA
[3] Univ Texas MD Anderson Canc Ctr, Houston, TX USA
[4] City Hope Natl Med Ctr, Monrovia, CA USA
[5] Vanderbilt Ingram Canc Ctr, Vanderbilt, TN USA
[6] Fred Hutchinson Canc Ctr, Sunnyside, WA USA
[7] Fox Chase Canc Ctr, Oreland, PA USA
[8] Univ Wisconsin, Carbone Canc Ctr, Madison, WI USA
[9] Univ Utah, Huntsman Canc Inst, Salt Lake City, UT USA
[10] Fred & Pamela Buffett Canc Ctr, Omaha, NE USA
[11] Indiana Univ, Melvin & Bren Simon Comprehens Canc Ctr, Indianapolis, IN USA
[12] UCLA Jonsson Comprehens Canc Ctr, Los Angeles, CA USA
[13] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA
[14] Barnes Jewish Hosp, Siteman Canc Ctr, St Louis, MO USA
[15] Washington Univ, Sch Med, St Louis, MO USA
[16] Univ Calif Davis, Comprehens Canc Ctr, Davis, CA USA
[17] Smilow Canc Hosp, Yale Canc Ctr, New Haven, CT USA
[18] Univ Michigan, Rogel Canc Ctr, Ann Arbor, MI USA
[19] Stanford Canc Inst, Stanford, CA USA
[20] Univ Hosp Seidman Canc Ctr, Case Comprehens Canc Ctr, Cleveland, OH USA
[21] Cleveland Clin, Taussig Canc Inst, Cleveland, OH USA
[22] UAB, ONeal Comprehens Canc Ctr, Birmingham, AL USA
[23] Univ Colorado, Ctr Canc, Denver, CO USA
[24] Dana Farber Canc Inst, Boston, MA USA
[25] Ohio State Univ, James Canc Hosp, Comprehens Canc Ctr, Columbus, OH USA
[26] Solove Res Inst, Columbus, OH USA
[27] Roswell Park Comprehens Canc Ctr, Buffalo, NY USA
[28] Mass Gen Canc Ctr, Waltham, MA USA
[29] Univ Calif San Diego, Moores Canc Ctr, San Diego, CA USA
[30] Mem Sloan Kettering Canc Ctr, New York, NY USA
[31] Univ Penn, Abramson Canc Ctr, Philadelphia, PA USA
[32] Univ Tennessee, Hlth Sci Ctr, Memphis, TN USA
[33] UChicago Med Comprehens Canc Ctr, Chicago, IL USA
[34] UT Southwestern Simmons Comprehens Canc Ctr, Dallas, TX USA
[35] Duke Canc Inst, Durham, NC USA
[36] Mayo Clin, Comprehens Canc Ctr, Jacksonville, FL USA
[37] Natl Comprehens Canc Network, Rockledge, PA USA
来源
JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK | 2024年 / 22卷 / 06期
关键词
ENDOSCOPIC SUBMUCOSAL DISSECTION; SHORT-COURSE RADIOTHERAPY; CLINICAL COMPLETE RESPONDERS; TOTAL MESORECTAL EXCISION; LONG-TERM OUTCOMES; WAIT-AND-SEE; NEOADJUVANT CHEMORADIOTHERAPY; LOCAL RECURRENCE; OPEN-LABEL; PREOPERATIVE CHEMORADIOTHERAPY;
D O I
10.6004/jnccn.2024.0042
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The determination of an optimal treatment plan for an individual patient with rectal cancer is a complex process. In addition to decisions relating to the intent of rectal cancer surgery (ie, curative or palliative), consideration must also be given to the likely functional results of treatment, including the probability of maintaining or restoring normal bowel function/anal continence and preserving genitourinary functions. Particularly for patients with distal rectal cancer, finding a balance between curative-intent therapy while having minimal impact on quality of life can be challenging. Furthermore, the risk of pelvic recurrence is higher in patients with rectal cancer compared with those with colon cancer, and locally recurrent rectal cancer is associated with a poor prognosis. Careful patient selection and the use of sequenced multimodality therapy following a multidisciplinary approach is recommended. These NCCN Guidelines Insights detail recent updates to the NCCN Guidelines for Rectal Cancer, including the addition of endoscopic submucosal dissection as an option for early- stage rectal cancer, updates to the total neoadjuvant therapy approach based on the results of recent clinical trials, and the addition of a "watch-and-wait" nonoperative management approach for clinical complete responders to neoadjuvant therapy.
引用
收藏
页码:366 / 375
页数:10
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