Influence of contrast medium on long-term renal function and outcomes in patients with septic acute kidney injury: A propensity-matched cohort study

被引：0

作者：

Kim, Jinnam ^{[1
,2
]}

Lee, Se Ju ^{[1
,3
]}

Kim, Jung Ho ^{[1
,4
]}

Ahn, Jin Young ^{[1
,4
]}

Jeong, Su Jin ^{[1
,4
]}

Choi, Jun Yong ^{[1
,4
]}

Yeom, Joon-Sup ^{[1
,4
]}

Oh, Hyung Jung ^{[5
]}

Chung, Yong Eun ^{[6
]}

Ku, Nam Su ^{[1
,4
]}

机构：

[1] Yonsei Univ, Coll Med, Dept Internal Med, 50-1 Yonseiro Ro, Seoul 03722, South Korea

[2] Hanyang Univ, Coll Med, Dept Internal Med, Seoul, South Korea

[3] Inha Univ, Coll Med, Dept Internal Med, Incheon, South Korea

[4] Yonsei Univ, Severance Hosp, AIDS Res Inst, Coll Med, 50-1 Yonseiro Ro, Seoul 03722, South Korea

[5] Sheikh Khalifa Specialty Hosp, Dept Nephrol, Al Shohadaa Rd,Exit 119, Ras Al Khaymah, U Arab Emirates

[6] Yonsei Univ, Coll Med, Dept Radiol, 50-1 Yonsei Ro, Seoul 03722, South Korea

来源：

JOURNAL OF CRITICAL CARE | 2024年 / 84卷

基金：

新加坡国家研究基金会;

关键词：

Acute kidney injury; Contrast media; Computed tomography; dialysis; Mortality; sepsis; SEVERE SEPSIS; MORTALITY; SHOCK; MANAGEMENT; DIAGNOSIS; THERAPY; FAILURE; IMPACT; SCORE; MYTH;

D O I：

10.1016/j.jcrc.2024.154898

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Purpose: To investigate the relationship between contrast medium administration and long-term mortality and renal function in patients with septic acute kidney injury (AKI). Materials and methods: We performed a retrospective, propensity-matched cohort study involving 1521 adult patients admitted with septic shock. Patients with septic AKI who underwent contrast or non-contrast CT scans were enrolled. The primary outcomes were the rates of 90-day mortality and dialysis within 90 days. The secondary outcomes included worsening of AKI, in-hospital mortality, and maintenance of dialysis after 90 days. Results: During the study period, 609 patients with septic AKI were identified; 220 (36.1%) underwent contrast CT and 389 (63.9%) underwent non-contrast CT. After propensity score matching, 133 pairs were obtained. There were no significant differences between the contrast and non-contrast CT groups in 90-day mortality (54.9% vs. 58.6%, P = 0.579), dialysis within 90 days (6.8% vs. 8.3%, P = 0.655), worsening AKI (2.3% vs. 3.0%, P = 0.706), in-hospital mortality (10.6% vs. 14.4%, P = 0.369), or maintenance of dialysis after 90 days (0.0% vs. 0.8%, P > 0.99). Conclusions: The administration of intravenous contrast medium was not associated with long-term mortality, deterioration of renal function, or dialysis in patients with septic AKI.

引用

页数：7