Genome-wide association studies reveal the genetic basis of growth and carcass traits in Sichuan Shelduck

被引:0
作者
Yang, Zhao [1 ]
Xi, Yang [1 ]
Qi, Jingjing [1 ]
Li, Liang [1 ]
Bai, Lili [1 ]
Zhang, Jun [2 ]
Lv, Jia [2 ]
Li, Bo [3 ]
Liu, Hehe [1 ]
机构
[1] Sichuan Agr Univ, Coll Anim Sci & Technol, Farm Anim Genet Resources Explorat & Innovat Key L, Chengdu 610000, Peoples R China
[2] Rural Revitalizat Dev Serv Ctr, Zigong, Peoples R China
[3] Farming Serv Ctr, Zigong, Rong County, Peoples R China
基金
国家重点研发计划;
关键词
GWAS; Sichuan Shelduck; growth; meat production performance; candidate gene; RELATIONSHIP MATRIX; ANAS-PLATYRHYNCHOS; SKELETAL-MUSCLE; SELECTION; DIFFERENTIATION; EXPRESSION; CBFA2T2; CELLS;
D O I
10.1016/j.psj.2024.104211
中图分类号
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号
0905 ;
摘要
China has abundant local duck resource populations, and evaluating the characteristics of these breeds will help improve development and utilization. In this study, we conducted the first investigations of growth and slaughter performance on Sichuan Shelduck (n = 240), an endangered duck local breed. The average body weight is 1497.91 g at 90 d of age. According to the growth curve through data recorded every 2 wk, we observed a low relative growth rate (RGR) for the early growth stage. The RGR shows a decreasing trend with age increasing in the stage from 0 to 56 d of age. The SNP-based heritability estimation showed the growth rate has a relatively high heritability, indicating high genetic stability for this trait. In the correlation analysis, the percentage of leg muscle is positively correlated with the absolute growth rate (AGR) at 28 to 42 d of age, whereas it is negatively correlated with the earlier stages, exhibiting a time-specific correlation result. Additionally, genome-wide association studies (GWAS) identified PCSK6, TOX2, , and TOMM7 7 as potential candidate genes influencing AGR (42-56) and AGR (56-90), while the candidate genes of slaughter traits were PTP4A2, FAM110B, TOX, UBXN2B, , and FCHSD2. . These results provide an important reference for further understanding the genetic basis of growth and meat production performance of Sichuan Shelduck.
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页数:12
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