Field-Directed Motion, Cargo Capture, and Closed-Loop Controlled Navigation of Microellipsoids

Microrobots have the potential for diverse applications, including targeted drug delivery and minimally invasive surgery. Despite advancements in microrobot design and actuation strategies, achieving precise control over their motion remains challenging due to the dominance of viscous drag, system disturbances, physicochemical heterogeneities, and stochastic Brownian forces. Here, a precise control over the interfacial motion of model microellipsoids is demonstrated using time-varying rotating magnetic fields. The impacts of microellipsoid aspect ratio, field characteristics, and magnetic properties of the medium and the particle on the motion are investigated. The role of mobile micro-vortices generated is highlighted by rotating microellipsoids in capturing, transporting, and releasing cargo objects. Furthermore, an approach is presented for controlled navigation through mazes based on real-time particle and obstacle sensing, path planning, and magnetic field actuation without human intervention. The study introduces a mechanism of directing motion of microparticles using rotating magnetic fields, and a control scheme for precise navigation and delivery of micron-sized cargo using simple microellipsoids as microbots. A precise control over the motion of prolate ellipsoid-shaped microrobots is achieved using rotating magnetic fields. The article demonstrates contactless capture, controlled transport, and targeted release of cargo particles and live cells, facilitated solely by hydrodynamic interactions. The close-loop control scheme further enables transport of cargo particles in complex microenvironments, such as a maze, without human intervention. image