Single-centre experience of implementing physiotherapist-led prehabilitation for chimeric antigen receptor T cell therapy

被引：0
作者：
McCourt, Orla [1 ,2 ]
Maciocia, Paul [1 ,2 ]
Roddie, Claire [1 ,2 ]
Hwang, Angela [1 ]
Wood, Leigh [1 ]
Panopoulou, Aikaterini [1 ]
Springell, Deborah Ann [1 ]
Al Bakir, Maise [1 ]
O'Reilly, Maeve [1 ]
机构：
[1] Univ Coll London Hosp NHS Fdn Trust, Dept Haematol, London, England
[2] Univ Coll London Canc Inst, Res Dept Haematol, London, England
来源：
EJHAEM | 2024年 / 5卷 / 05期
关键词：
chimeric antigen receptor T-cell therapy; exercise; physiotherapy; rehabilitation;
D O I：
10.1002/jha2.1006
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Introduction: This report outlines the evaluation of physiotherapist-led prehabilitation/rehabilitation for recipients of chimeric antigen receptor T (CAR-T) cell therapy. Methods: A hybrid approach was used, incorporating in-person assessment of quality of life and functional capacity (6-min walk test and timed sit-to-stand test), and a personalised home exercise programme with remotely delivered physiotherapist support pre/post-admission. Results: Functional deficits were prevalent at referral for CAR-T. Prehabilitation and rehabilitation were highly acceptable to patients, and improvements in functional capacity were documented pre-admission. Conclusion: This data highlights the importance of pre-CAR-T functional assessment and prehabilitation to optimise preparation and recovery.
引用
收藏
页码：1033 / 1037
页数：5
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