Exploring the Pharmacological Effects of Bioactive Peptides on Human Nervous Disorders: A Comprehensive Review

被引:0
作者
Singh, Kuldeep [1 ]
Gupta, Jeetendra Kumar [1 ]
Shrivastava, Aman [2 ]
Jain, Divya [3 ]
Yadav, Amrendra Pratap [4 ]
Dwivedi, Sumeet [5 ]
Dubey, Anubhav [6 ]
Kumar, Shivendra [1 ]
机构
[1] GLA Univ, Inst Pharmaceut Res, Dept Pharmacol, Mathura, Uttar Pradesh, India
[2] Coll Pharm, Inst Profess Studies, Dept Pharmacol, Gwalior, MP, India
[3] Uttaranchal Univ, Sch Appl & Life Sci, Dept Microbiol, Dehra Dun, Uttarakhand, India
[4] Meerut Inst Technol, Dept Pharm, Meerut, UP, India
[5] Acropolis Inst Pharmaceut Educ & Res, Dept Pharmacognosy, Indore, MP, India
[6] Maharana Pratap Coll Pharm, Dept Pharmacol, Kanpur, Uttar Pradesh, India
关键词
Bioactive peptides; focal ischemia; inflammation; blood-brain barrier permeability; neurodegenerative diseases; FOCAL CEREBRAL-ISCHEMIA; NF-KAPPA-B; CELL-PENETRATING PEPTIDES; RECEPTOR-BINDING DOMAIN; BLOOD-BRAIN-BARRIER; OXIDATIVE STRESS; IN-VITRO; PROTEIN; DELIVERY; REPERFUSION;
D O I
10.2174/0118715273316382240807120241
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
A family of peptides known as bioactive peptides has unique physiological properties and may be used to improve human health and prevent illness. Because bioactive peptides impact the immunological, endocrine, neurological, and cardiovascular systems, they have drawn a lot of interest from researchers. According to recent studies, bioactive peptides have a lot to offer in the treatment of inflammation, neuronal regeneration, localized ischemia, and the blood-brain barrier. It investigates various peptide moieties, including antioxidative properties, immune response modulation, and increased blood-brain barrier permeability. It also looks at how well they work as therapeutic candidates and finds promising peptide-based strategies for better outcomes. Furthermore, it underscores the need for further studies to support their clinical utility and suggests that results from such investigations will enhance our understanding of the pathophysiology of these conditions. In order to understand recent advances in BPs and to plan future research, academic researchers and industrial partners will find this review article to be a helpful resource.
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收藏
页码:32 / 46
页数:15
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