Screening and Preparation of a Short Chain Antimicrobial Peptide SFPAS

被引：0

作者：

Guo, Yuan-Yuan ^{[1
]}

Cong, Hai-Lin ^{[1
,2
]}

Shen, You-Qing ^{[1
]}

Niu, Qing-Hai ^{[3
]}

Yu, Bing ^{[1
]}

机构：

[1] Qingdao Univ, Inst Biomed Mat & Engn, Coll Chem & Chem Engn, Coll Mat Sci & Engn,State Key Lab Biofibers & Ecot, Qingdao, Peoples R China

[2] Shandong Univ Technol, Sch Mat Sci & Engn, Qingdao, Peoples R China

[3] Linyi Kangli Med Devices Co Ltd, Dept R&D, Linyi, Peoples R China

来源：

INTEGRATED FERROELECTRICS | 2024年 / 240卷 / 02期

基金：

中国国家自然科学基金;

关键词：

Antimicrobial peptide; cell membrane chromatographic fillers; bacterial infections;

D O I：

10.1080/10584587.2024.2322355

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

A short chain antimicrobial peptide SFPAS was screened by cell membrane chromatography combined with one bead and one object method. The membrane chromatographic fillers with particle size of about 2 mu m were prepared. Through field emission scanning electron microscope observation, we could see the successful preparation of membrane chromatographic packing. Then, the antibacterial activity of antimicrobial peptides was tested, and it was found that the selected antimicrobial peptides had obvious antibacterial activity and could effectively kill Staphylococcus aureus and Escherichia coli.

引用

页码：383 / 387

页数：5

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