Updates in Molecular Profiling of Pancreatic Ductal Adenocarcinoma

被引:0
|
作者
Lee, Jaewon James [1 ]
Yeh, Jen Jen [1 ,2 ,3 ]
机构
[1] Univ North Carolina Chapel Hill, Dept Surg, 170 Manning Dr,CB7213, Chapel Hill, NC 27599 USA
[2] Univ North Carolina Chapel Hill, Dept Pharmacol, Chapel Hill, NC USA
[3] Univ North Carolina Chapel Hill, Lineberger Comprehens Canc Ctr, 450 West Dr,CB7295, Chapel Hill, NC 27599 USA
关键词
Pancreatic cancer; Molecular subtyping; Cancer genomics; Next-generation sequencing; Precision oncology; CANCER; SUBTYPES; FIBROBLASTS; KRAS(G12D); INHIBITION; FOLFIRINOX; EFFICACY;
D O I
10.1016/j.suc.2024.04.001
中图分类号
R61 [外科手术学];
学科分类号
摘要
[No abstract available]
引用
收藏
页码:939 / 950
页数:12
相关论文
共 50 条
  • [31] Molecular pathogenesis of pancreatic ductal adenocarcinoma and clinical implications
    Magee, CJ
    Greenhalf, W
    Howes, N
    Ghaneh, P
    Neoptolemos, JP
    SURGICAL ONCOLOGY-OXFORD, 2001, 10 (1-2): : 1 - 23
  • [32] The limits of molecular signatures for pancreatic ductal adenocarcinoma subtyping
    Lautizi, Manuela
    Baumbach, Jan
    Weichert, Wilko
    Steiger, Katja
    List, Markus
    Pfarr, Nicole
    Kacprowski, Tim
    NAR CANCER, 2022, 4 (04):
  • [33] Molecular pathogenesis of precursor lesions of pancreatic ductal adenocarcinoma
    Biankin, AV
    Kench, JG
    Dijkman, FP
    Biankin, SA
    Henshall, SM
    PATHOLOGY, 2003, 35 (01) : 14 - 24
  • [34] Molecular alterations and targeted therapy in pancreatic ductal adenocarcinoma
    Yunzhen Qian
    Yitao Gong
    Zhiyao Fan
    Guopei Luo
    Qiuyi Huang
    Shengming Deng
    He Cheng
    Kaizhou Jin
    Quanxing Ni
    Xianjun Yu
    Chen Liu
    Journal of Hematology & Oncology, 13
  • [35] Comprehensive molecular profiling of paired patient samples of primary and metastatic (met) pancreatic ductal adenocarcinoma (PDAC).
    Trivedi, Neel
    Feldman, Rebecca
    Wang, Hongkun
    Karki, Nabin Raj
    Marshall, John
    Weinberg, Benjamin Adam
    JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (15)
  • [36] Spatial proteomic immune profiling of pancreatic ductal adenocarcinoma and the tumor microenvironment
    Yeung, Jason
    Bai, Yunhao
    Yeo, Yao Yu
    Qiu, Huaying
    Zhu, Bokai
    Heij, Lara R.
    Abu Shah, Enas
    Nolan, Garry P.
    Sivakumar, Shivan
    Jiang, Sizun
    CANCER RESEARCH, 2024, 84 (02)
  • [37] Plasma Metabolome Profiling Identifies Metabolic Subtypes of Pancreatic Ductal Adenocarcinoma
    Mahajan, Ujjwal Mukund
    Alnatsha, Ahmed
    Li, Qi
    Oehrle, Bettina
    Weiss, Frank-Ulrich
    Sendler, Matthias
    Distler, Marius
    Uhl, Waldemar
    Fahlbusch, Tim
    Goni, Elisabetta
    Beyer, Georg
    Chromik, Ansgar
    Bahra, Markus
    Klein, Fritz
    Pilarsky, Christian
    Gruetzmann, Robert
    Lerch, Markus M.
    Lauber, Kirsten
    Christiansen, Nicole
    Kamlage, Beate
    Regel, Ivonne
    Mayerle, Julia
    CELLS, 2021, 10 (07)
  • [38] Dysbindin as a novel biomarker for pancreatic ductal adenocarcinoma identified by proteomic profiling
    Guo, Xin
    Lv, Xiaohui
    Fang, Cheng
    Lv, Xing
    Wang, Fengsong
    Wang, Dongmei
    Zhao, Jun
    Ma, Yueyun
    Xue, Yu
    Bai, Quan
    Yao, Xuebiao
    Chen, Yong
    INTERNATIONAL JOURNAL OF CANCER, 2016, 139 (08) : 1821 - 1829
  • [39] Resolution of Novel Pancreatic Ductal Adenocarcinoma Subtypes by Global Phosphotyrosine Profiling
    Humphrey, Emily S.
    Su, Shih-Ping
    Nagrial, Adnan M.
    Hochgraefe, Falko
    Pajic, Marina
    Lehrbach, Gillian M.
    Parton, Robert G.
    Yap, Alpha S.
    Horvath, Lisa G.
    Chang, David K.
    Biankin, Andrew V.
    Wu, Jianmin
    Daly, Roger J.
    MOLECULAR & CELLULAR PROTEOMICS, 2016, 15 (08) : 2671 - 2685
  • [40] Pancreatic ductal adenocarcinoma
    Gallmeier, E.
    Gress, T. M.
    INTERNIST, 2018, 59 (08): : 805 - 822