Organizational challenges for partial heart transplantation

被引:0
|
作者
Alexander, Vincent S. [1 ,2 ]
Vogel, Andrew D. [1 ,2 ]
Silvano, Zachary T. [1 ,2 ]
Javed, Herra [1 ]
Mitta, Alekhya [1 ,3 ]
Rajab, Taufiek Konrad [1 ]
机构
[1] Arkansas Childrens Hosp, Dept Cardiovasc Surg, 1 Childrens Way, Little Rock, AR 72202 USA
[2] Alabama Coll Osteopath Med, Div Res, 445 Hlth Sci Blvd, Dothan, AL 36303 USA
[3] Univ South Carolina, Div Res, 1705 Coll St,Close-Hipp Suite 552, Columbia, SC 29208 USA
基金
美国国家卫生研究院;
关键词
cryopreservation; donor heart allocation; ethical considerations; immunosuppression; partial heart transplantation; pediatric cardiac transplantation; AORTIC-VALVE-REPLACEMENT; FUTURE;
D O I
10.1080/14796678.2024.2404775
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Partial heart transplantation (PHT) has emerged as a new treatment strategy to correct unrepairable heart valve dysfunction in pediatric patients. PHT selectively replaces the dysfunctional components of the recipient's heart and spares the native ventricles. As a result, the transplant biology of PHTs differs from heart transplants. Notably, donor hearts that are unsuitable for whole heart transplantation can be used, graft preservation can be prolonged and immunosuppression levels can be lowered. These nuances of PHT transplant biology have important implications for organizational aspects of PHT clinical application.
引用
收藏
页码:719 / 728
页数:10
相关论文
共 50 条
  • [1] The future of partial heart transplantation
    Rajab, Taufiek K.
    Vogel, Andrew D.
    Alexander, Vincent S.
    Brockbank, Kelvin G. M.
    Turek, Joseph W.
    JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2024, 43 (06) : 863 - 865
  • [2] Animal models for partial heart transplantation
    Yerger, Julia
    Hill, Morgan A.
    Fitzgerald, David C.
    Rajab, Taufiek K.
    PEDIATRIC TRANSPLANTATION, 2024, 28 (04)
  • [3] Partial Heart Transplantation in Adult Cardiac Surgery
    Sherard, Curry
    Bisbee, Cora
    Konsek, Haley
    Kang, Lillian
    Turek, Joseph W.
    Rajab, Taufiek K.
    INNOVATIONS-TECHNOLOGY AND TECHNIQUES IN CARDIOTHORACIC AND VASCULAR SURGERY, 2023, 18 (02) : 126 - 131
  • [4] Donor supply for partial heart transplantation in the United States
    Quintao, Ritchelli
    Kwon, Jennie H.
    Bishara, Katherine
    Rajab, Taufiek Konrad
    CLINICAL TRANSPLANTATION, 2023, 37 (10)
  • [5] Why partial heart transplantation could be regulated as organ transplantation
    Glazier, Alexandra K.
    Dafflisio, Gianna
    Rajab, Taufiek Konrad
    Kalfa, David
    Jaggers, James
    Emani, Sitaram
    Greenwald, Melissa A.
    AMERICAN JOURNAL OF TRANSPLANTATION, 2024, 24 (11) : 1941 - 1949
  • [6] Partial heart transplantation: Growing heart valve implants for children
    Rajab, Taufiek Konrad
    ARTIFICIAL ORGANS, 2024, 48 (04) : 326 - 335
  • [7] Current challenges in pediatric heart transplantation for congenital heart disease
    Kirklin, James K.
    CURRENT OPINION IN ORGAN TRANSPLANTATION, 2015, 20 (05) : 577 - 583
  • [8] Immunosuppression following heart transplantation: prospects and challenges
    Chang, David H.
    Kittleson, Michelle M.
    Kobashigawa, Jon A.
    IMMUNOTHERAPY, 2014, 6 (02) : 181 - 194
  • [9] Organizational structure and processes in pediatric heart transplantation: A survey of practices
    Stendahl, Gail
    Bobay, Kathleen
    Berger, Stuart
    Zangwill, Steven
    PEDIATRIC TRANSPLANTATION, 2012, 16 (03) : 257 - 264
  • [10] Challenges in Heart Transplantation in the Era of COVID-19
    DeFilippis, Ersilia M.
    Farr, Maryjane A.
    Givertz, Michael M.
    CIRCULATION, 2020, 141 (25) : 2048 - 2051