Immune checkpoint inhibitors for first-line treatment of advanced esophageal squamous cell carcinoma

被引:0
作者
Alsina, Maria [1 ]
Fleitas-Kanonnikoff, Tania [2 ]
机构
[1] Hosp Univ Navarra, Med Oncol Dept, Translat Med Oncol Invest Grp, Navarrabiomed IdiSNA, C-Irunlarrea 3, Pamplona 35008, Spain
[2] Hosp Clin Univ Valencia, Med Oncol Dept, INCLIVA, Valencia, Spain
来源
MED | 2024年 / 5卷 / 09期
关键词
CHEMOTHERAPY; PLACEBO;
D O I
10.1016/j.medj.2024.05.016
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Immunotherapy has revolutionized the treatment landscape of esophageal squamous cell carcinoma. He et al. present the final results of the randomized phase 3 ESCORT-1st trial, confirming positive survival outcomes when adding the anti-PD1 inhibitor camrelizumab to first-line chemotherapy treatment in Chinese patients with esophageal squamous cell cancer.(1)
引用
收藏
页码:1038 / 1040
页数:3
相关论文
共 10 条
[1]   Integrative immune transcriptomic classification improves patient selection for precision immunotherapy in advanced gastro-oesophageal adenocarcinoma [J].
Cabeza-Segura, Manuel ;
Gambardella, Valentina ;
Gimeno-Valiente, Francisco ;
Antonio Carbonell-Asins, Juan ;
Alarcon-Molero, Lorena ;
Gonzalez-Vilanova, Arturo ;
Zuniga-Trejos, Sheila ;
Rentero-Garrido, Pilar ;
Villagrasa, Rosana ;
Gil, Mireia ;
Dura, Ana ;
Richart, Paula ;
Alonso, Noelia ;
Huerta, Marisol ;
Rosello, Susana ;
Roda, Desamparados ;
Tarazona, Noelia ;
Martinez-Ciarpaglini, Carolina ;
Castillo, Josefa ;
Cervantes, Andres ;
Fleitas, Tania .
BRITISH JOURNAL OF CANCER, 2022, 127 (12) :2198-2206
[2]   Nivolumab Combination Therapy in Advanced Esophageal Squamous-Cell Carcinoma [J].
Doki, Y. ;
Ajani, J. A. ;
Kato, K. ;
Xu, J. ;
Wyrwicz, L. ;
Motoyama, S. ;
Ogata, T. ;
Kawakami, H. ;
Hsu, C. -H. ;
Adenis, A. ;
El Hajbi, F. ;
Di Bartolomeo, M. ;
Braghiroli, M. I. ;
Holtved, E. ;
Ostoich, S. A. ;
Kim, H. R. ;
Ueno, M. ;
Mansoor, W. ;
Yang, W. -C. ;
Liu, T. ;
Bridgewater, J. ;
Makino, T. ;
Xynos, I. ;
Liu, X. ;
Lei, M. ;
Kondo, K. ;
Patel, A. ;
Gricar, J. ;
Chau, I. ;
Kitagawa, Y. .
NEW ENGLAND JOURNAL OF MEDICINE, 2022, 386 (05) :449-462
[3]   Final analysis of camrelizumab plus chemotherapy for untreated advanced or metastatic esophageal squamous cell carcinoma: The ESCORT-1st trial [J].
He, Mingming ;
Wang, Zhiqiang ;
Lu, Jin ;
Bai, Yuxian ;
Mao, Teng ;
Wang, Jun ;
Fan, Qingxia ;
Zhang, Yiping ;
Zhao, Kuaile ;
Chen, Zhendong ;
Gao, Shegan ;
Li, Jiancheng ;
Fu, Zhichao ;
Gu, Kangsheng ;
Liu, Zhihua ;
Wu, Lin ;
Zhang, Xiaodong ;
Feng, Jifeng ;
Niu, Zuoxing ;
Ba, Yi ;
Zhang, Helong ;
Liu, Ying ;
Zhang, Li ;
Min, Xuhong ;
Huang, Jing ;
Cheng, Ying ;
Wang, Dong ;
Sheng, Zhen ;
Zeng, Wanqin ;
Song, Li ;
Xu, Rui-Hua ;
Luo, Huiyan .
MED, 2024, 5 (09) :1137-1149.e3
[4]   Tertiary Lymphoid Structure-Associated B Cells Enhance Response to Programmed Cell Death Protein 1 Blockade in Cancer Immunotherapy [J].
Hu, Chupeng ;
You, Wenhua ;
Kong, Deyuan ;
Huang, Yedi ;
Lu, Jinying ;
Zhao, Mengya ;
Jin, Yu ;
Peng, Rui ;
Hua, Dong ;
Kuang, Dong-Ming ;
Chen, Yun .
GASTROENTEROLOGY, 2024, 166 (06) :1069-1084
[5]   Sex differences in immune responses [J].
Klein, Sabra L. ;
Flanagan, Katie L. .
NATURE REVIEWS IMMUNOLOGY, 2016, 16 (10) :626-638
[6]   Effect of Camrelizumab vs Placebo Added to Chemotherapy on Survival and Progression-Free Survival in Patients With Advanced or Metastatic Esophageal Squamous Cell Carcinoma: The ESCORT-1st Randomized Clinical Trial [J].
Luo, Huiyan ;
Lu, Jin ;
Bai, Yuxian ;
Mao, Teng ;
Wang, Jun ;
Fan, Qingxia ;
Zhang, Yiping ;
Zhao, Kuaile ;
Chen, Zhendong ;
Gao, Shegan ;
Li, Jiancheng ;
Fu, Zhichao ;
Gu, Kangsheng ;
Liu, Zhihua ;
Wu, Lin ;
Zhang, Xiaodong ;
Feng, Jifeng ;
Niu, Zuoxing ;
Ba, Yi ;
Zhang, Helong ;
Liu, Ying ;
Zhang, Li ;
Min, Xuhong ;
Huang, Jing ;
Cheng, Ying ;
Wang, Dong ;
Shen, Yu ;
Yang, Qing ;
Zou, Jianjun ;
Xu, Rui-Hua .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2021, 326 (10) :916-925
[7]   Cancer and the Microbiome-Influence of the Commensal Microbiota on Cancer, Immune Responses, and Immunotherapy [J].
Matson, Vyara ;
Chervin, Carolina Soto ;
Gajewski, Thomas F. .
GASTROENTEROLOGY, 2021, 160 (02) :600-613
[8]   Oesophageal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up [J].
Obermannova, R. ;
Alsina, M. ;
Cervantes, A. ;
Leong, T. ;
Lordick, F. ;
Nilsson, M. ;
van Grieken, N. C. T. ;
Vogel, A. ;
Smyth, E. C. .
ANNALS OF ONCOLOGY, 2022, 33 (10) :992-1004
[9]   Pembrolizumab plus chemotherapy versus chemotherapy alone for first-line treatment of advanced oesophageal cancer (KEYNOTE-590): a randomised, placebo-controlled, phase 3 study [J].
Sun, Jong-Mu ;
Shen, Lin ;
Shah, Manish A. ;
Enzinger, Peter ;
Adenis, Antoine ;
Doi, Toshihiko ;
Kojima, Takashi ;
Metges, Jean-Philippe ;
Li, Zhigang ;
Kim, Sung-Bae ;
Cho, Byoung Chul ;
Mansoor, Wasat ;
Li, Shau-Hsuan ;
Sunpaweravong, Patrapim ;
Maqueda, Maria Alsina ;
Goekkurt, Eray ;
Hara, Hiroki ;
Antunes, Luis ;
Fountzilas, Christos ;
Tsuji, Akihito ;
Oliden, Victor Castro ;
Liu, Qi ;
Shah, Sukrut ;
Bhagia, Pooja ;
Kato, Ken .
LANCET, 2021, 398 (10302) :759-771
[10]   Tislelizumab plus chemotherapy versus placebo plus chemotherapy as first-line treatment for advanced or metastatic oesophageal squamous cell carcinoma (RATIONALE-306): a global, randomised, placebo-controlled, phase 3 study [J].
Xu, Jianming ;
Kato, Ken ;
Raymond, Eric ;
Hubner, Richard A. ;
Shu, Yongqian ;
Pan, Yueyin ;
Park, Sook Ryun ;
Ping, Lu ;
Jiang, Yi ;
Zhang, Jingdong ;
Wu, Xiaohong ;
Yao, Yuanhu ;
Shen, Lin ;
Kojima, Takashi ;
Gotovkin, Evgeny ;
Ishihara, Ryu ;
Wyrwicz, Lucjan ;
Van Cutsem, Eric ;
Jimenez-Fonseca, Paula ;
Lin, Chen -Yuan ;
Wang, Lei ;
Shi, Jingwen ;
Li, Liyun ;
Yoon, Harry H. .
LANCET ONCOLOGY, 2023, 24 (05) :483-495