Unravelling Peptic Ulcers: Comprehensive Insights into Etiology, Diagnosis, Screening Techniques, and Treatment

被引:1
作者
Pathak, Rashmi [1 ,2 ]
Chandra, Phool [1 ]
Sachan, Neetu [3 ]
机构
[1] Teerthanker Mahaveer Univ, Teerthanker Mahaveer Coll Pharm, Moradabad 244001, Uttar Pradesh, India
[2] Invertis Univ, Dept Pharm, Bareilly 243123, Uttar Pradesh, India
[3] Maharana Pratap Coll Pharm, Kanpur 209217, Uttar Pradesh, India
关键词
Ulcer models; peptic ulcer; epidemiology; Helicobacter pylori; diagnosis; screening techniques; HELICOBACTER-PYLORI INFECTION; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; RECEPTOR ANTAGONIST USE; GASTRIC-MUCOSAL INJURY; PROTON PUMP INHIBITORS; UREA BREATH TEST; GASTROINTESTINAL-TRACT; TRIPLE THERAPY; RISK-FACTORS; ACID-SECRETION;
D O I
10.2174/0113816128310979240828102727
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The risk of illnesses is increasing in the modern era due to unhealthy and modern lifestyles. Research has shown that the most frequent acid-induced abrasion, which often occurs in the stomach and proximal duodenum, is gastric and Peptic Ulcer Disease (PUD), which is a primary worldwide health concern. The deformity is characterized by denuded mucosa and spreads into the submucosa. Non-steroidal antiinflammatory drugs (NSAIDs) and H. pylori infections are two common offenders. In the past, it has been thought that dietary variables, stress, and an acidic hypersecretory state encourage mucosal disruption in peptic acid disease patients. Peptic ulcers continue to be a significant health issue because of their potential for substantial consequences, including bleeding, blockage, and perforation, even with advancements in detection and treatment. This review discusses current screening methods for peptic ulcers and the challenges in diagnosis and treatment, emphasizing the need for precise diagnosis and more effective therapies.
引用
收藏
页码:2065 / 2084
页数:20
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