ObjectivesThis study aimed to assess the diagnostic performance of a support vector machine (SVM) algorithm for acute cholecystitis and evaluate its effectiveness in accurately diagnosing this condition.MethodsUsing a retrospective analysis of patient data from a single center, individuals with abdominal pain lasting one week or less were included. The SVM model was trained and optimized using standard procedures. Model performance was assessed through sensitivity, specificity, accuracy, and AUC-ROC, with probability calibration evaluated using the Brier score.ResultsAmong 534 patients, 198 (37.07%) were diagnosed with acute cholecystitis. The SVM model showed balanced performance, with a sensitivity of 83.08% (95% CI: 71.73-91.24%), a specificity of 80.21% (95% CI: 70.83-87.64%), and an accuracy of 81.37% (95% CI: 74.48-87.06%). The positive predictive value (PPV) was 73.97% (95% CI: 65.18-81.18%), the negative predictive value (NPV) was 87.50% (95% CI: 80.19-92.37%), and the AUC-ROC was 0.89 (95% CI: 0.85 to 0.93). The Brier score indicated well-calibrated probability estimates.ConclusionThe SVM algorithm demonstrated promising potential for accurately diagnosing acute cholecystitis. Further refinement and validation are needed to enhance its reliability in clinical practice.
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Univ Ottawa, Dept Emergency Med, Ottawa, ON, CanadaUniv British Columbia, Dept Emergency Med, 910 West 10th Ave, Vancouver, BC V5Z 1M9, Canada
Meehan, Andrew
Li, Henry
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Univ Alberta, Fac Med & Dent, Dept Emergency Med, Edmonton, AB, Canada
Univ Alberta, Fac Med & Dent, Dept Pediat, Div Pediat Neurol, Edmonton, AB, CanadaUniv British Columbia, Dept Emergency Med, 910 West 10th Ave, Vancouver, BC V5Z 1M9, Canada
Li, Henry
Goel, Gautam
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Queensway Carleton Hosp, Dept Emergency Med, Ottawa, ON, Canada
Johns Hopkins Univ, Whiting Sch Engn, Baltimore, MD USAUniv British Columbia, Dept Emergency Med, 910 West 10th Ave, Vancouver, BC V5Z 1M9, Canada
Goel, Gautam
Masood, Sameer
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Univ Toronto, Dept Med, Toronto, ON, Canada
Univ Hlth Network, Toronto Gen Hosp Res Inst, Toronto, ON, CanadaUniv British Columbia, Dept Emergency Med, 910 West 10th Ave, Vancouver, BC V5Z 1M9, Canada
Masood, Sameer
Grant, Lars
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McGill Univ, Dept Emergency Med, Montreal, PQ, Canada
Lady Davis Inst Med Res, Montreal, PQ, CanadaUniv British Columbia, Dept Emergency Med, 910 West 10th Ave, Vancouver, BC V5Z 1M9, Canada
Grant, Lars
Ben-Yakov, Maxim
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Univ Toronto, Dept Med, Toronto, ON, Canada
Univ Hlth Network, Toronto Gen Hosp Res Inst, Toronto, ON, CanadaUniv British Columbia, Dept Emergency Med, 910 West 10th Ave, Vancouver, BC V5Z 1M9, Canada
Ben-Yakov, Maxim
Michalowski, Wojtek
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Univ Ottawa, Telfer Sch Management, Ottawa, ON, CanadaUniv British Columbia, Dept Emergency Med, 910 West 10th Ave, Vancouver, BC V5Z 1M9, Canada
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Yonsei Univ, Coll Med, Dept Biomed Syst Informat, 331 Dongbaekjukjeon daero, Seoul 16995, South KoreaYonsei Univ, Coll Med, Dept Biomed Syst Informat, 331 Dongbaekjukjeon daero, Seoul 16995, South Korea
Han, Changho
Jung, Yun Jung
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Ajou Univ, Sch Med, Dept Pulmonol & Crit Care Med, 164 World Cup Ro, Suwon 16499, South KoreaYonsei Univ, Coll Med, Dept Biomed Syst Informat, 331 Dongbaekjukjeon daero, Seoul 16995, South Korea
Jung, Yun Jung
Park, Ji Eun
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Ajou Univ, Sch Med, Dept Pulmonol & Crit Care Med, 164 World Cup Ro, Suwon 16499, South KoreaYonsei Univ, Coll Med, Dept Biomed Syst Informat, 331 Dongbaekjukjeon daero, Seoul 16995, South Korea
Park, Ji Eun
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Chung, Wou Young
Yoon, Dukyong
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Yonsei Univ, Coll Med, Dept Biomed Syst Informat, 331 Dongbaekjukjeon daero, Seoul 16995, South Korea
Severance Hosp, Inst Innovat Digital Healthcare IIDH, Seoul, South Korea
Yonsei Univ Hlth Syst, Yongin Severance Hosp, Ctr Digital Hlth, Yongin, South KoreaYonsei Univ, Coll Med, Dept Biomed Syst Informat, 331 Dongbaekjukjeon daero, Seoul 16995, South Korea
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Chiang Mai Univ, Fac Med, Dept Emergency Med, Chiang Mai 50200, ThailandChiang Mai Univ, Fac Med, Dept Emergency Med, Chiang Mai 50200, Thailand
Faikhongngoen, Saowaluck
Chenthanakij, Boriboon
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Chiang Mai Univ, Fac Med, Dept Emergency Med, Chiang Mai 50200, ThailandChiang Mai Univ, Fac Med, Dept Emergency Med, Chiang Mai 50200, Thailand
Chenthanakij, Boriboon
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Wittayachamnankul, Borwon
Phinyo, Phichayut
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Chiang Mai Univ, Fac Med, Dept Family Med, Chiang Mai 50200, Thailand
Chiang Mai Univ, Fac Med, Ctr Clin Epidemiol & Clin Stat, Chiang Mai 50200, ThailandChiang Mai Univ, Fac Med, Dept Emergency Med, Chiang Mai 50200, Thailand