A Complex Condition; Polycystic Ovary Syndrome (PCOS): A Review of its Recent Advanced Treatment

被引:0
作者
Wal, Pranay [1 ]
Saxena, Bhagawati [2 ]
Aziz, Namra [1 ]
Pyne, Chandana [1 ]
Wal, Ankita [1 ]
Rathore, Shruti [3 ]
机构
[1] PSIT Pranveer Singh Inst Technol Pharm, Kanpur 209305, Uttar Pradesh, India
[2] Nirma Univ, Inst Pharm, Dept Pharmacol, SG Highway, Ahmadabad 382481, India
[3] LCIT Sch Pharm, Bilaspur 495220, Chhattisgarh, India
关键词
Polycystic ovaries; obesity; hormonal imbalance; infertility; hirusitism; menstrual cycle; N-ACETYL-CYSTEINE; LIFE-STYLE MODIFICATION; IN-VITRO FERTILIZATION; INSULIN-RESISTANCE; BARIATRIC SURGERY; CLOMIPHENE CITRATE; OBESE-PATIENTS; DOUBLE-BLIND; AROMATASE INHIBITORS; METFORMIN TREATMENT;
D O I
10.2174/0115734048259334231020120628
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder affecting women worldwide. It refers to a condition that often has 'poly' liquid containing sacks around ovaries. It affects reproductive-aged females, giving rise to menstrual and related reproductive issues. PCOS is marked by hormonal imbalance, often resulting in hyperandrogenism. Women with PCOS might experience abnormal insulin activity and complications such as acne, mood swings, hirsutism, obesity, and infertility. The disease is linked with severe clinical ailments such as type 2 diabetes (T2DM), cardiovascular diseases (CVDs), and cancer. A faulty lifestyle, neuroendocrine factors, genetic causes, and androgen exposures often cause PCOS. The approach of society towards physiological problems such as PCOS in women is that it must be under the veil that is the ultimate barrier to the early diagnosis of PCOS. Thus, this review summarizes the causes, symptoms, pathophysiology, diagnosis, and possible treatment (medical, herbal, and lifestyle improvement, acupuncture, and bariatric surgery) related to PCOS.
引用
收藏
页数:18
相关论文
共 168 条
[71]  
Jain Priyanka, 2013, J Hum Reprod Sci, V6, P253, DOI 10.4103/0974-1208.126295
[72]   Dietary management of women with polycystic ovary syndrome in the United Kingdom: the role of dietitians [J].
Jeanes, Y. M. ;
Barr, S. ;
Smith, K. ;
Hart, K. H. .
JOURNAL OF HUMAN NUTRITION AND DIETETICS, 2009, 22 (06) :551-558
[73]  
Kar Sujata, 2012, J Hum Reprod Sci, V5, P262, DOI 10.4103/0974-1208.106338
[74]   The Effect of Glucagon-Like Peptide-1 Receptor Agonist Therapy on Body Mass Index in Adolescents With Severe Obesity A Randomized, Placebo-Controlled, Clinical Trial [J].
Kelly, Aaron S. ;
Rudser, Kyle D. ;
Nathan, Brandon M. ;
Fox, Claudia K. ;
Metzig, Andrea M. ;
Coombes, Brandon J. ;
Fitch, Angela K. ;
Bomberg, Eric M. ;
Abuzzahab, M. Jennifer .
JAMA PEDIATRICS, 2013, 167 (04) :355-360
[75]   Genetic Basis of Polycystic Ovary Syndrome (PCOS): Current Perspectives [J].
Khan, Muhammad Jaseem ;
Ullah, Anwar ;
Basit, Sulman .
APPLICATION OF CLINICAL GENETICS, 2019, 12 :249-260
[76]  
Kharb S., 2021, Ann. Clin. Lab. Res, V9, P351
[77]   Does supplementation of in-vitro culture medium with melatonin improve IVF outcome in PCOS? [J].
Kim, Mi Kyoung ;
Park, Eun A. ;
Kim, Hyung Joon ;
Choi, Won Yun ;
Cho, Jung Hyun ;
Lee, Woo Sik ;
Cha, Kwang Yul ;
Kim, You Shin ;
Lee, Dong Ryul ;
Yoon, Tae Ki .
REPRODUCTIVE BIOMEDICINE ONLINE, 2013, 26 (01) :22-29
[78]   Statins in the treatment of polycystic ovary syndrome [J].
Kodaman, Pinar H. ;
Duleba, Antoni J. .
SEMINARS IN REPRODUCTIVE MEDICINE, 2008, 26 (01) :127-138
[79]   Genetics of the polycystic ovary syndrome [J].
Kosova, Gueluem ;
Urbanek, Margrit .
MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2013, 373 (1-2) :29-38
[80]   The benefits of finasteride for hirsute women with polycystic ovary syndrome or idiopathic hirsutism [J].
Lakryc, EM ;
Motta, ELA ;
Soares, JM ;
Haidar, MA ;
de Lima, GR ;
Baracat, EC .
GYNECOLOGICAL ENDOCRINOLOGY, 2003, 17 (01) :57-63