Case report: Supraglottic SCC with sphenoid and cavernous sinus metastases

Introduction & importance: Primary Sino-nasal metastases are rare. The most common anatomical sites that metastasise to this region are the kidneys followed by the lungs, breast, thyroid and prostate. Metastases from laryngeal cancer are even rarer. We report a unique case of sphenoid and cavernous sinus metastases in a patient with glottic cancer. Herein we describe to the authors' knowledge the first reported case of supraglottic metastases to the sphenoid and cavernous sinus. This study will help further our understanding metastatic spread outside of those well described in literature. Case presentation: A 75-year-old with a right neck swelling and hoarseness, treated for glottic SCC and represented with cranial nerve involvement suspicious for sinonasal metastases. Clinical discussion: Metastases to the sinonasal cavity are rare representing 3 % of head and neck malignancies. The most common primary sites include breast, colon, thyroid and prostate. Metastases from the larynx are exceedingly rare. Conclusion This case report illustrates a rare case of Sino-nasal metastases from a patient with glottic SCC, it highlights an alternative metastatic pathway which often proves fatal.