Advances in Medicine: Photodynamic Therapy

被引:10
|
作者
Aebisher, David [1 ]
Szpara, Jakub [2 ]
Bartusik-Aebisher, Dorota [3 ]
机构
[1] Rzeszow Univ, Med Coll, Dept Photomed & Phys Chem, PL-35025 Rzeszow, Poland
[2] Rzeszow Univ, Med Coll, English Div Sci Club, PL-35025 Rzeszow, Poland
[3] Rzeszow Univ, Med Coll, Dept Biochem & Gen Chem, PL-35025 Rzeszow, Poland
关键词
photodynamic therapy; photosensitizers; history of photodynamic therapy; in vitro; in vivo; nanotechnology; development; cancer therapies; CELL-DEATH; IN-SITU; PDT; CANCER; PHOTOSENSITIZERS; TUMOR; MECHANISMS; HISTORY; CHEMOTHERAPY; CARCINOMA;
D O I
10.3390/ijms25158258
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Over the past decades, medicine has made enormous progress, revolutionized by modern technologies and innovative therapeutic approaches. One of the most exciting branches of these developments is photodynamic therapy (PDT). Using a combination of light of a specific wavelength and specially designed photosensitizing substances, PDT offers new perspectives in the fight against cancer, bacterial infections, and other diseases that are resistant to traditional treatment methods. In today's world, where there is a growing problem of drug resistance, the search for alternative therapies is becoming more and more urgent. Imagine that we could destroy cancer cells or bacteria using light, without the need to use strong chemicals or antibiotics. This is what PDT promises. By activating photosensitizers using appropriately adjusted light, this therapy can induce the death of cancer or bacterial cells while minimizing damage to surrounding healthy tissues. In this work, we will explore this fascinating method, discovering its mechanisms of action, clinical applications, and development prospects. We will also analyze the latest research and patient testimonies to understand the potential of PDT for the future of medicine.
引用
收藏
页数:22
相关论文
共 50 条
  • [41] Advances in Optical Imaging for Monitoring Photodynamic Therapy Dosimetry
    Li Wenbo
    Shen Yi
    Li Buhong
    CHINESE JOURNAL OF LASERS-ZHONGGUO JIGUANG, 2020, 47 (02):
  • [42] Research advances in the use of tetrapyrrolic photosensitizers for photodynamic therapy
    Nyman, ES
    Hynninen, PH
    JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 2004, 73 (1-2) : 1 - 28
  • [43] Advances in Optical Imaging for Monitoring Photodynamic Therapy Dosimetry
    Li W.
    Shen Y.
    Li B.
    Zhongguo Jiguang/Chinese Journal of Lasers, 2020, 47 (02):
  • [44] Multiporphyrinic architectures: Advances in structural design for photodynamic therapy
    Gao, Yuwei
    Li, Yan
    Xu, Zhengwei
    Yu, Shuangjiang
    Liu, Junqiu
    Sun, Hongcheng
    AGGREGATE, 2024, 5 (01):
  • [45] Theranostics with photodynamic therapy for personalized medicine: to see and to treat
    Wang, Youchao
    Staudinger, Johannes Nikodemus
    Mindt, Thomas L.
    Gasser, Gilles
    THERANOSTICS, 2023, 13 (15): : 5501 - 5544
  • [46] An Update on Recent Advances of Photodynamic Therapy for Primary Cutaneous Lymphomas
    Liu, Wei-Ting
    Wang, Han-Tang
    Yeh, Yi-Hsuan
    Wong, Tak-Wah
    PHARMACEUTICS, 2023, 15 (05)
  • [47] Recent advances in noble metal complex based photodynamic therapy
    Wu, Yanping
    Li, Shumeng
    Chen, Yuncong
    He, Weijiang
    Guo, Zijian
    CHEMICAL SCIENCE, 2022, 13 (18) : 5085 - 5106
  • [48] Recent advances and trends in nanoparticles based photothermal and photodynamic therapy
    Kadkhoda, Jamileh
    Tarighatnia, Ali
    Barar, Jaleh
    Aghanejad, Ayuob
    Davaran, Soodabeh
    PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, 2022, 37
  • [49] Nanotechnology-Based Photodynamic Therapy: Concepts, Advances, and Perspectives
    Garg, Tarun
    Jain, Nitin
    Rath, Goutam
    Goyal, Amit K.
    CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS, 2015, 32 (05): : 389 - 439
  • [50] Photodynamic therapy for prostate cancer: Recent advances, challenges and opportunities
    Xue, Qin
    Zhang, Jingliang
    Jiao, Jianhua
    Qin, Weijun
    Yang, Xiaojian
    FRONTIERS IN ONCOLOGY, 2022, 12