Advances in Medicine: Photodynamic Therapy

被引:21
作者
Aebisher, David [1 ]
Szpara, Jakub [2 ]
Bartusik-Aebisher, Dorota [3 ]
机构
[1] Rzeszow Univ, Med Coll, Dept Photomed & Phys Chem, PL-35025 Rzeszow, Poland
[2] Rzeszow Univ, Med Coll, English Div Sci Club, PL-35025 Rzeszow, Poland
[3] Rzeszow Univ, Med Coll, Dept Biochem & Gen Chem, PL-35025 Rzeszow, Poland
关键词
photodynamic therapy; photosensitizers; history of photodynamic therapy; in vitro; in vivo; nanotechnology; development; cancer therapies; CELL-DEATH; IN-SITU; PDT; CANCER; PHOTOSENSITIZERS; TUMOR; MECHANISMS; HISTORY; CHEMOTHERAPY; CARCINOMA;
D O I
10.3390/ijms25158258
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Over the past decades, medicine has made enormous progress, revolutionized by modern technologies and innovative therapeutic approaches. One of the most exciting branches of these developments is photodynamic therapy (PDT). Using a combination of light of a specific wavelength and specially designed photosensitizing substances, PDT offers new perspectives in the fight against cancer, bacterial infections, and other diseases that are resistant to traditional treatment methods. In today's world, where there is a growing problem of drug resistance, the search for alternative therapies is becoming more and more urgent. Imagine that we could destroy cancer cells or bacteria using light, without the need to use strong chemicals or antibiotics. This is what PDT promises. By activating photosensitizers using appropriately adjusted light, this therapy can induce the death of cancer or bacterial cells while minimizing damage to surrounding healthy tissues. In this work, we will explore this fascinating method, discovering its mechanisms of action, clinical applications, and development prospects. We will also analyze the latest research and patient testimonies to understand the potential of PDT for the future of medicine.
引用
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页数:22
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