Unusual cause of dyspnea in patient with Myelofibrosis: The Ruxolitinib lung

被引:0
作者
El Kik, Antoine [1 ]
Vander Kuylen, Maarten [2 ]
Bailly, Benjamin [3 ]
Fallas, Jennifer [4 ]
Bondue, Benjamin [1 ]
机构
[1] Univ Libre Bruxelles, Hop Univ Bruxelles, Dept Pneumol, Brussels, Belgium
[2] Univ Libre Bruxelles, Hop Univ Bruxelles, Dept Thorac Surg, Brussels, Belgium
[3] Hop Louviere S Jolimont, Dept Hematol, Haine St Paul, Belgium
[4] Univ Libre Bruxelles, Hop Univ Bruxelles, Dept Pathol, Brussels, Belgium
关键词
Mycobacterium avium; Myelofibrosis; Pulmonary alveolar proteinosis; Ruxolitinib;
D O I
10.1016/j.rmcr.2024.102090
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Although pulmonary complications are frequent in patients suffering from hematological diseases, secondary pulmonary alveolar proteinosis is a very rare complication of myelofibrosis. We describe the case of a 65-year-old male patient treated by Ruxolitinib for myelofibrosis who developed a secondary pulmonary alveolar proteinosis complicated by a Mycobacterium avium infection. We believe that this respiratory complication might be related to the myelofibrosis and to the initiation of the Ruxolitinib according to its temporal relationship. Pulmonologists should be aware that respiratory symptoms in myelofibrosis patients taking Ruxolitinib may be related to pulmonary alveolar proteinosis.
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页数:4
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