computational fluid dynamics;
finite element on unstructured meshes;
nasal airflow;
parallel processing;
SLEEP-APNEA;
CHILDREN;
SIMULATION;
D O I:
10.1002/eng2.12972
中图分类号:
TP39 [计算机的应用];
学科分类号:
081203 ;
0835 ;
摘要:
Adenoid obstruction is a prevalent condition that can significantly alter nasal airflow patterns, leading to various respiratory symptoms. This study aims to explore the influence of adenoid obstruction on human nasal airflow using computational fluid dynamics (CFD) simulations. We developed a realistic nasal cavity model to simulate both steady-state inhalation and transient breathing cycles, accounting for various levels of obstruction. The three-dimensional, incompressible Navier-Stokes equations were discretized employing a stabilized P1-P1$$ P1-P1 $$ finite element method on unstructured meshes, along with an implicit second-order backward differentiation formula. The numerical solution was obtained using a Newton-Krylov-Schwarz algorithm-based parallel solver. Our findings indicate that obstruction of the adenoid cross-sectional area below 50% minimally affects nasal airflow, whereas noticeable changes occurred as obstructions exceeded the 50% threshold. Complete blockage was observed at levels greater than 70%, and inhalation difficulties could arise even at the 50% obstruction mark during stimulation or extreme inhalation scenarios. These results substantiate the clinical guidelines that advocate a 50% obstruction ratio as the demarcation between conservative treatment and surgery. Furthermore, this study offers valuable insights into the intricate relationship between the adenoid obstruction and nasal airflow, potentially enhancing clinical decision-making in the diagnosis and treatment of nasal obstruction. We investigated the impact of adenoid obstruction on human nasal airflow using computational fluid simulations. By developing a realistic nasal cavity model and employing advanced numerical methods, the study demonstrates that obstruction levels below 50% minimally affect airflow, while noticeable changes occur beyond this threshold. These findings support clinical guidelines recommending surgery for obstructions surpassing 50%, providing valuable insights for enhancing diagnosis and treatment of nasal obstruction. image
机构:
Westmead Hosp, Dept Otolaryngol Head & Neck Surg, Sydney, NSW, AustraliaWestmead Hosp, Dept Otolaryngol Head & Neck Surg, Sydney, NSW, Australia
Senanayake, Praween
Warfield-McAlpine, Patrick
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h-index: 0
机构:
RMIT Univ, Sch Engn, Melbourne, Vic, AustraliaWestmead Hosp, Dept Otolaryngol Head & Neck Surg, Sydney, NSW, Australia
Warfield-McAlpine, Patrick
Salati, Hana
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h-index: 0
机构:
RMIT Univ, Sch Engn, Melbourne, Vic, AustraliaWestmead Hosp, Dept Otolaryngol Head & Neck Surg, Sydney, NSW, Australia
Salati, Hana
Bradshaw, Kimberley
论文数: 0引用数: 0
h-index: 0
机构:
Westmead Hosp, Dept Otolaryngol Head & Neck Surg, Sydney, NSW, AustraliaWestmead Hosp, Dept Otolaryngol Head & Neck Surg, Sydney, NSW, Australia
Bradshaw, Kimberley
Wong, Eugene
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h-index: 0
机构:
Westmead Hosp, Dept Otolaryngol Head & Neck Surg, Sydney, NSW, AustraliaWestmead Hosp, Dept Otolaryngol Head & Neck Surg, Sydney, NSW, Australia
Wong, Eugene
Inthavong, Kiao
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h-index: 0
机构:
RMIT Univ, Sch Engn, Melbourne, Vic, AustraliaWestmead Hosp, Dept Otolaryngol Head & Neck Surg, Sydney, NSW, Australia
Inthavong, Kiao
Singh, Narinder
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h-index: 0
机构:
Westmead Hosp, Dept Otolaryngol Head & Neck Surg, Sydney, NSW, Australia
Univ Sydney, Sydney Med Sch, Camperdown, NSW, AustraliaWestmead Hosp, Dept Otolaryngol Head & Neck Surg, Sydney, NSW, Australia
机构:
Capital Med Univ, Beijing Tongren Hosp, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R ChinaCapital Med Univ, Beijing Tongren Hosp, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R China
Li, Lifeng
Zang, Hongrui
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h-index: 0
机构:
Capital Med Univ, Beijing Tongren Hosp, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R ChinaCapital Med Univ, Beijing Tongren Hosp, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R China
Zang, Hongrui
Han, Demin
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h-index: 0
机构:
Capital Med Univ, Beijing Tongren Hosp, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R ChinaCapital Med Univ, Beijing Tongren Hosp, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R China
Han, Demin
Ramanathan, Murugappan, Jr.
论文数: 0引用数: 0
h-index: 0
机构:
Johns Hopkins Sch Med, Dept Otolaryngol Head & Neck Surg, 6th Floor,601 N Caroline St, Baltimore, MD 21287 USACapital Med Univ, Beijing Tongren Hosp, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R China
Ramanathan, Murugappan, Jr.
Carrau, Ricardo L.
论文数: 0引用数: 0
h-index: 0
机构:
Ohio State Univ, Dept Otolaryngol Head & Neck Surg, James Canc Hosp, Wexner Med Ctr, Columbus, OH 43210 USACapital Med Univ, Beijing Tongren Hosp, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R China
Carrau, Ricardo L.
London, Nyall R., Jr.
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机构:
Johns Hopkins Sch Med, Dept Otolaryngol Head & Neck Surg, 6th Floor,601 N Caroline St, Baltimore, MD 21287 USA
Natl Inst Deafness & Other Commun Disorders, NIH, Bethesda, MD USACapital Med Univ, Beijing Tongren Hosp, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R China
机构:
Capital Med Univ, Beijing Tongren Hosp, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R ChinaCapital Med Univ, Beijing Tongren Hosp, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R China
Li, Lifeng
Zang, Hongrui
论文数: 0引用数: 0
h-index: 0
机构:
Capital Med Univ, Beijing Tongren Hosp, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R ChinaCapital Med Univ, Beijing Tongren Hosp, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R China
Zang, Hongrui
Han, Demin
论文数: 0引用数: 0
h-index: 0
机构:
Capital Med Univ, Beijing Tongren Hosp, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R ChinaCapital Med Univ, Beijing Tongren Hosp, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R China
Han, Demin
London, Nyall R., Jr.
论文数: 0引用数: 0
h-index: 0
机构:
Johns Hopkins Sch Med, Dept Otolaryngol Head & Neck Surg, 601 N Caroline St,6th Floor, Baltimore, MD 21205 USA
NIDCD, NIH, Bethesda, MD USACapital Med Univ, Beijing Tongren Hosp, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R China
机构:
Virginia Commonwealth Univ, Dept Otolaryngol Head & Neck Surg, Sch Med, Med Coll Virginia Campus, Richmond, VA 23298 USAVirginia Commonwealth Univ, Dept Otolaryngol Head & Neck Surg, Sch Med, Med Coll Virginia Campus, Richmond, VA 23298 USA
Alam, Suhyla
Li, Chengyu
论文数: 0引用数: 0
h-index: 0
机构:
Ohio State Univ, Dept Otolaryngol Head & Neck Surg, Columbus, OH 43210 USA
Villanova Univ, Dept Mech Engn, Villanova, PA 19085 USAVirginia Commonwealth Univ, Dept Otolaryngol Head & Neck Surg, Sch Med, Med Coll Virginia Campus, Richmond, VA 23298 USA
Li, Chengyu
Bradburn, Kathryn H.
论文数: 0引用数: 0
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机构:
Med Univ South Carolina, Charleston, SC 29425 USAVirginia Commonwealth Univ, Dept Otolaryngol Head & Neck Surg, Sch Med, Med Coll Virginia Campus, Richmond, VA 23298 USA
Bradburn, Kathryn H.
Zhao, Kai
论文数: 0引用数: 0
h-index: 0
机构:
Ohio State Univ, Dept Otolaryngol Head & Neck Surg, Columbus, OH 43210 USA
Ohio State Univ, Dept Biomed Engn, Columbus, OH 43210 USAVirginia Commonwealth Univ, Dept Otolaryngol Head & Neck Surg, Sch Med, Med Coll Virginia Campus, Richmond, VA 23298 USA
Zhao, Kai
Lee, Thomas S.
论文数: 0引用数: 0
h-index: 0
机构:
Virginia Commonwealth Univ, Dept Otolaryngol Head & Neck Surg, Sch Med, Med Coll Virginia Campus, Richmond, VA 23298 USAVirginia Commonwealth Univ, Dept Otolaryngol Head & Neck Surg, Sch Med, Med Coll Virginia Campus, Richmond, VA 23298 USA
机构:
Sun Yat Sen Univ, Otorhinolaryngol Inst, Affiliated Hosp 1, Otorhinolaryngol Hosp, Guangzhou 510080, Guangdong, Peoples R ChinaSun Yat Sen Univ, Otorhinolaryngol Inst, Affiliated Hosp 1, Otorhinolaryngol Hosp, Guangzhou 510080, Guangdong, Peoples R China
Xiong, G-X
Zhan, J-M
论文数: 0引用数: 0
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机构:
Sun Yat Sen Univ, Dept Mech, Guangzhou 510275, Guangdong, Peoples R ChinaSun Yat Sen Univ, Otorhinolaryngol Inst, Affiliated Hosp 1, Otorhinolaryngol Hosp, Guangzhou 510080, Guangdong, Peoples R China
Zhan, J-M
Zuo, K-J
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机构:
Sun Yat Sen Univ, Otorhinolaryngol Inst, Affiliated Hosp 1, Otorhinolaryngol Hosp, Guangzhou 510080, Guangdong, Peoples R ChinaSun Yat Sen Univ, Otorhinolaryngol Inst, Affiliated Hosp 1, Otorhinolaryngol Hosp, Guangzhou 510080, Guangdong, Peoples R China
Zuo, K-J
Rong, L-W
论文数: 0引用数: 0
h-index: 0
机构:
Sun Yat Sen Univ, Dept Mech, Guangzhou 510275, Guangdong, Peoples R ChinaSun Yat Sen Univ, Otorhinolaryngol Inst, Affiliated Hosp 1, Otorhinolaryngol Hosp, Guangzhou 510080, Guangdong, Peoples R China
Rong, L-W
Li, J-F
论文数: 0引用数: 0
h-index: 0
机构:
Sun Yat Sen Univ, Dept Mech, Guangzhou 510275, Guangdong, Peoples R ChinaSun Yat Sen Univ, Otorhinolaryngol Inst, Affiliated Hosp 1, Otorhinolaryngol Hosp, Guangzhou 510080, Guangdong, Peoples R China
Li, J-F
Xu, G.
论文数: 0引用数: 0
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机构:
Sun Yat Sen Univ, Otorhinolaryngol Inst, Affiliated Hosp 1, Otorhinolaryngol Hosp, Guangzhou 510080, Guangdong, Peoples R ChinaSun Yat Sen Univ, Otorhinolaryngol Inst, Affiliated Hosp 1, Otorhinolaryngol Hosp, Guangzhou 510080, Guangdong, Peoples R China