Visible-light-induced palladium-catalyzed formal [3+3] cyclization of 2-iodophenols and cyclopropenes

被引：0
|
作者：
Niu, Yue-Jie [1 ,2 ]
Gao, Shu-Xin [1 ,2 ]
Liu, Xin-Xin [1 ,2 ]
Xin, Hong [1 ,2 ]
Duan, Xin-Hua [1 ,2 ]
Guo, Li-Na [1 ,2 ]
Gao, Pin [1 ,2 ]
Li, Pengfei [1 ,2 ,3 ,4 ]
机构：
[1] Xi An Jiao Tong Univ, Sch Chem, Dept Chem, Xian Key Lab Sustainable Energy Mat Chem, Xian 710049, Peoples R China
[2] Xi An Jiao Tong Univ, MOE Key Lab Nonequilibrium Synth & Modulat Condens, Xian 710049, Peoples R China
[3] Xi An Jiao Tong Univ, Frontier Inst Sci & Technol, Xian 710049, Peoples R China
[4] Xi An Jiao Tong Univ, State Key Lab Mech Behav Mat, Xian 710049, Peoples R China
来源：
ORGANIC CHEMISTRY FRONTIERS | 2024年 / 11卷 / 21期
基金：
中国国家自然科学基金;
关键词：
RADICAL-ADDITION; CHROMENES; ANNULATION; ETHERS;
D O I：
10.1039/d4qo01400f
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A visible-light-induced palladium-catalyzed formal [3 + 3] cyclization of 2-iodophenols and cyclopropenes is presented. This protocol provides a facile approach for the synthesis of 2,2-disubstituted 2H-chromenes with a quaternary carbon center in moderate to good yields. A catalytic cycle involving an aryl radical addition and an intramolecular palladium-catalyzed C-O coupling is proposed for this transformation. Visible-light-induced palladium-catalyzed formal [3 + 3] cyclization of 2-iodophenols and cyclopropenes for the synthesis of 2,2-disubstituted 2H-chromenes with a quaternary carbon center in moderate to good yields.
引用
收藏
页码：6194 / 6199
页数：6
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