Successful Treatment and Long-Term Follow-Up of Parry-Romberg Syndrome with Anterolateral Thigh Adipofascial Flap

Background:Anterolateral thigh adipofascial free flap transfer is a frequently used method to reconstruct facial symmetry and restore facial soft-tissue contour in patients with Parry-Romberg syndrome, but long-term prognosis and outcomes are unclear.Method:The authors report their treatment experience with 42 patients between 2001 and 2017 using microsurgical free anterolateral thigh adipofascial flap transfer. Long-term follow-up results and final reconstructive outcomes were evaluated.Results:A total of 42 patients were included. The follow-up ranged from 5 to 21 years. All patients were satisfied with the surgery. Photographic evaluation revealed significant enhancement of postoperative appearance. Numbness or hypesthesia of the local area was the most common symptom noted in long-term follow-up.Conclusions:This study evaluated the long-term results of treating Parry-Romberg disease with microsurgery using ALT free flap in the authors' department. Over 20 years of experience and the significant enhancement in overall appearance indicate a long-lasting, excellent outcome.CLINICAL QUESTION/LEVEL OF EVIDENCE:Therapeutic, IV.