MI2AMI-CS: A meta-analysis comparing Impella and IABP outcomes in Acute Myocardial Infarction-related Cardiogenic Shock

被引：7

作者：

De Ferrari, Tommaso ^{[1
]}

Pistelli, Lorenzo ^{[1
]}

Franzino, Marco ^{[1
]}

Molinero, Agustin Ezequiel ^{[1
]}

Santis, Giulia Azzurra De ^{[1
]}

Di Carlo, Alessandro ^{[1
]}

Vetta, Giampaolo ^{[2
]}

Parlavecchio, Antonio ^{[1
]}

Fimiani, Luigi ^{[3
]}

Picci, Andrea ^{[3
]}

Certo, Giuseppe ^{[1
]}

Parisi, Francesca ^{[4
]}

Venuti, Giuseppe ^{[3
]}

机构：

[1] Univ Messina, Dept Clin & Expt Med, Cardiol Unit, Azienda Osped Univ Policlin G Martino, Messina, Italy

[2] Vrije Univ Brussel, Univ Ziekenhuis Brussel, Postgrad Program Cardiac Electrophysiol & Pacing, European Reference Networks Guard Heart,Heart Rhyt, Ave Laerbeek 101, B-1090 Brussels, Belgium

[3] Papardo Hosp, Dept Cardiovasc Dis, Intervent Cardiol Unit, Messina, Italy

[4] Ist Mediterraneo & Trapianti & Terapie ad Alta Spe, Palermo, Italy

来源：

INTERNATIONAL JOURNAL OF CARDIOLOGY | 2024年 / 414卷

关键词：

Cardiogenic shock; Acute myocardial infarction; Percutaneous mechanical circulatory support; Intra-aortic balloon pump; Impella; Major bleeding; Mortality; Adverse events; SUPPORT; PUMP;

D O I：

10.1016/j.ijcard.2024.132411

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background: Cardiogenic Shock (CS) complicating acute myocardial infarction (AMI) poses a significant mortality risk, suggesting the opportunity to implement effective mechanical circulatory support strategies. The comparative efficacy of Intra-Aortic Balloon Pump (IABP) and Impella in managing CS-AMI remains a subject of investigation. Objective: This meta-analysis aims to evaluate the comparative effectiveness of Impella and IABP in managing CS-AMI, exploring mortality and adverse events. Methods: A systematic search of major databases from inception to November 2023 identified eight studies, comprising 10,628 patients, comparing Impella and IABP in CS-AMI. Retrospective studies (preferably Propensity-matched) and Randomized Clinical Trials (RCTs) were included. Results: Impella use exhibited significantly higher mortality (57% vs. 46%; OR: 1.44, 95% CI: 1.29-1.60; p < 0.001) and major bleeding (30% vs 15%; OR: 2.93, 95% CI: 1.67-5.13; p < 0.001). Conclusions: In unselected CS-AMI patients, Impella usage is associated with significantly higher mortality and major bleeding.

引用

页数：7

共 23 条

[1] Impella versus IABP in acute myocardial infarction complicated by cardiogenic shock [J].

Alushi, Brunilda ;

Douedari, Andel ;

Froehlig, Georg ;

Knie, Wulf ;

Wurster, Thomas H. ;

Leistner, David M. ;

Staehli, Barbara-Elisabeth ;

Mochmann, Hans-Christian ;

Pieske, Burkert ;

Landmesser, Ulf ;

Krackhardt, Florian ;

Skurk, Carsten .

OPEN HEART, 2019, 6 (01)

[2] The Evolving Landscape of Impella Use in the United States Among Patients Undergoing Percutaneous Coronary Intervention With Mechanical Circulatory Support [J].

Amin, Amit P. ;

Spertus, John A. ;

Curtis, Jeptha P. ;

Desai, Nihar ;

Masoudi, Frederick A. ;

Bach, Richard G. ;

McNeely, Christian ;

Al-Badarin, Firas ;

House, John A. ;

Kulkarni, Hemant ;

Rao, Sunil, V .

CIRCULATION, 2020, 141 (04) :273-284

[3] Hemodynamics of Mechanical Circulatory Support [J].

Burkhoff, Daniel ;

Sayer, Gabriel ;

Doshi, Darshan ;

Uriel, Nir .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2015, 66 (23) :2664-2674

[4] 2023 ESC Guidelines for the management of acute coronary syndromes [J].

Byrne, Robert A. ;

Rossello, Xavier ;

Coughlan, J. J. ;

Barbato, Emanuele ;

Berry, Colin ;

Chieffo, Alaide ;

Claeys, Marc J. ;

Dan, Gheorghe-Andrei ;

Dweck, Marc R. ;

Galbraith, Mary ;

Gilard, Martine ;

Hinterbuchner, Lynne ;

Jankowska, Ewa A. ;

Juni, Peter ;

Kimura, Takeshi ;

Kunadian, Vijay ;

Leosdottir, Margret ;

Lorusso, Roberto ;

Pedretti, Roberto F. E. ;

Rigopoulos, Angelos G. ;

Gimenez, Maria Rubini ;

Thiele, Holger ;

Vranckx, Pascal ;

Wassmann, Sven ;

Wenger, Nanette Kass ;

Ibanez, Borja ;

ESC Sci Document Grp .

EUROPEAN HEART JOURNAL, 2023, 44 (38) :3720-3826

[5] The novel cystatin C, lactate, interleukin-6, and N-terminal pro-B-type natriuretic peptide (CLIP)-based mortality risk score in cardiogenic shock after acute myocardial infarction [J].

Ceglarek, Uta ;

Schellong, Paul ;

Rosolowski, Maciej ;

Scholz, Markus ;

Willenberg, Anja ;

Kratzsch, Juergen ;

Zeymer, Uwe ;

Fuernau, Georg ;

De Waha-Thiele, Suzanne ;

Buettner, Petra ;

Jobs, Alexander ;

Freund, Anne ;

Desch, Steffen ;

Feistritzer, Hans-Josef ;

Isermann, Berend ;

Thiery, Joachim ;

Poess, Janine ;

Thiele, Holger .

EUROPEAN HEART JOURNAL, 2021, 42 (24) :2344-2352

[6] Association of Use of an Intravascular Microaxial Left Ventricular Assist Device vs Intra-aortic Balloon Pump With In-Hospital Mortality and Major Bleeding Among Patients With Acute Myocardial Infarction Complicated by Cardiogenic Shock [J].

Dhruva, Sanket S. ;

Ross, Joseph S. ;

Mortazavi, Bobak J. ;

Hurley, Nathan C. ;

Krumholz, Harlan M. ;

Curtis, Jeptha P. ;

Berkowitz, Alyssa ;

Masoudi, Frederick A. ;

Messenger, John C. ;

Parzynski, Craig S. ;

Ngufor, Che ;

Girotra, Saket ;

Amin, Amit P. ;

Shah, Nilay D. ;

Desai, Nihar R. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2020, 323 (08) :734-745

[7] Comparative Healthcare Resource Utilization of Percutaneous Mechanical Circulatory Support Using Impella Versus Intra-aortic Balloon Pump Use for Patients With Acute Coronary Syndrome and Cardiogenic Shock Undergoing Percutaneous Coronary Interventions: Insights From National Inpatient Sample [J].

Dodoo, Sheriff N. ;

Kwapong, Yaa Adoma ;

Agyemang-Sarpong, Alicia ;

Amoran, Emmanuel ;

Egolum, Ugochukwu O. ;

Ghasemzadeh, Nima ;

Ramadan, Ronnie ;

Henry, Glen ;

Samady, Habib .

CURRENT PROBLEMS IN CARDIOLOGY, 2024, 49 (01)

[8] Comparison of ECMO vs ECpella in PatientsWith Non-Post-Pericardiotomy Cardiogenic Shock: An Updated Meta-Analysis [J].

Iannaccone, Mario ;

Venuti, Giuseppe ;

di Simone, Emanuela ;

De Filippo, Ovidio ;

Bertaina, Maurizio ;

Colangelo, Salvatore ;

Boccuzzi, Giacomo ;

de Piero, Maria Elena ;

Attisani, Matteo ;

Barbero, Umberto ;

Zanini, Paola ;

Livigni, Sergio ;

Noussan, Patrizia ;

D'Ascenzo, Fabrizio ;

de Ferrari, Gaetano Maria ;

Porto, Italo ;

Truesdell, Alexander G. .

CARDIOVASCULAR REVASCULARIZATION MEDICINE, 2022, 40 :134-141

[9] Cardiogenic Shock Classification to Predict Mortality in the Cardiac Intensive Care Unit [J].

Jentzer, Jacob C. ;

van Diepen, Sean ;

Barsness, Gregory W. ;

Henry, Timothy D. ;

Menon, Venu ;

Rihal, Charanjit S. ;

Naidu, Srihari S. ;

Baran, David A. .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2019, 74 (17) :2117-2128

[10] Primary left ventricular unloading with delayed reperfusion in patients with anterior ST-elevation myocardial infarction: Rationale and design of the STEMI-DTU randomized pivotal trial br [J].

Kapur, Navin K. ;

Kim, Raymond J. ;

Moses, Jeffrey W. ;

Stone, Gregg W. ;

Udelson, James E. ;

Ben-Yehuda, Ori ;

Redfors, Bjorn ;

Issever, Melek Ozgu ;

Josephy, Noam ;

Polak, Samantha J. ;

O'Neill, William W. .

AMERICAN HEART JOURNAL, 2022, 254 :122-132

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