A novel fluorescent probe based on coumarin and triazole for monitoring fluoride ions in the substitution reaction

In this paper, a novel coumarin-based fluorescent probe (8-acetyl-3-(2H-benzo[d][1,2,3]triazol-2-yl)-7-((tertbutyldimethylsilyl)oxy)-2H-chromen-2-one, CTA5) was designed and synthesized for monitoring the process of some reaction involving fluoride ions. CTA5 has a strong fluorescent emission peak at 451 nm, and the emission peak is red-shifted to 517 nm after the reaction with fluoride ions and CTA5 has also good selectivity and linear relationship for fluoride ions detection. Furthermore, CTA5 was applied to monitor the change of fluoride ions concentration in some substitution reactions, and the end of the reaction can be judged by the equilibrium of fluoride ion concentration. The experimental results show that it is feasible to use fluorescence signal to monitor the progress of the reaction.