Precision nutrition-based strategy for management of human diseases and healthy aging: current progress and challenges forward

被引:2
|
作者
Singh, Vipin Kumar [1 ]
Hu, Xiao-Hu [2 ]
Singh, Amit Kishore [3 ]
Solanki, Manoj Kumar [4 ]
Vijayaraghavan, Pooja [5 ]
Srivastav, Rajpal [5 ]
Joshi, Naveen Kumar [6 ]
Kumari, Madhuree [7 ]
Singh, Sandeep Kumar [8 ]
Wang, Zhen [2 ]
Kumar, Ajay [5 ]
机构
[1] KS Saket PG Coll, Dept Bot, Ayodhya, India
[2] Yulin Normal Univ, Agr Coll, Guangxi Key Lab Agr Resources Chem & Biotechnol, Yulin 537000, Peoples R China
[3] TM Bhagalpur Univ, BN Coll, Bot Dept, Bhagalpur, India
[4] IES Univ, Dept Life Sci & Biol Sci, Bhopal, Madhya Pradesh, India
[5] Amity Univ, Amity Inst Biotechnol, Noida, India
[6] Amity Univ, Amity Inst Microbial Biotechnol, Noida, India
[7] Indian Inst Sci, Dept Biochem, Bengaluru, India
[8] Indian Agr Res Inst, Dept Microbiol, New Delhi, India
来源
FRONTIERS IN NUTRITION | 2024年 / 11卷
关键词
biomarker; microbiota; bioactive constituents; machine learning; algorithm; immunity; CARDIOVASCULAR-DISEASE; MEDITERRANEAN DIET; PERSONALIZED NUTRITION; NUTRIGENOMICS; PREVENTION; RISK; INTERVENTIONS; METAANALYSIS; DEPRESSION; SYMPTOMS;
D O I
10.3389/fnut.2024.1427608
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Currently, the treatment of various human ailments is based on different therapeutic approaches including traditional and modern medicine systems. Precision nutrition has come into existence as an emerging approach considering the diverse aspects such as age, sex, genetic and epigenetic makeup, apart from the pathophysiological conditions. The continuously and gradually evolving disciplines of genomics about nutrition have elucidated the importance of genetic variations, epigenetic information, and expression of myriads of genes in disease progression apart from the involvement in modulating therapeutic responses. Further, the investigations have presented the considerable role of gut microbiota comprising of commensal and symbionts performing innumerable activities such as release of bioactive molecules, defense against pathogenic microbes, and regulation of immunity. Noteworthy, the characteristics of the microbiome change depending on host attributes, environmental factors, and habitat, in addition to diet, and therefore can be employed as a biomarker to unravel the response to given food. The specific diet and the components thereof can be suggested for supporting the enrichment of the desired microbial community to some extent as an important part of precision nutrition to achieve not only the goal of human health but also of healthy aging.
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页数:11
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