Endoscopic Ultrasound-Guided Fine Needle Biopsy of Focal Liver Lesions: An Effective Mini-Invasive Alternative to the Percutaneous Approach

被引:0
作者
Rancatore, Gabriele [1 ]
Ligresti, Dario [1 ]
Rizzo, Giacomo Emanuele Maria [1 ,2 ]
Carrozza, Lucio [1 ]
Traina, Mario [1 ]
Tarantino, Ilaria [1 ]
机构
[1] IRCCS ISMETT, Dept Diagnost & Therapeut Serv, Endoscopy Serv, I-90127 Palermo, Italy
[2] Univ Palermo, Dept Hlth Promot Mother & Child Care, Sect Gastroenterol & Hepatol, Internal Med & Med Specialties,PROMISE, I-90121 Palermo, Italy
关键词
EUS; liver; tumor; lesion; FNB; HEPATOCELLULAR-CARCINOMA; EUROPEAN-SOCIETY; EUS; ASPIRATION; DIAGNOSIS; CORE; METASTASES; BENIGN;
D O I
10.3390/diagnostics14131336
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Despite the introduction of serological neoplastic biomarkers and typical radiological characteristics in clinical practice, liver biopsy (LB) is often still necessary to establish a histological diagnosis, especially in ambiguous cases. Nowadays, LB via the percutaneous approach (PC-LB), under computed tomography (CT) scan or ultrasonography (US) guidance, is the route of choice. However, certain focal liver lesions can be challenging to access percutaneously. In such cases, endoscopic ultrasound (EUS)-guided fine needle biopsy (FNB) may represent an attractive, minimally invasive alternative. This retrospective observational study aimed to evaluate the efficacy, diagnostic performance, and safety of EUS-FNB conducted on 58 focal liver lesions located in both liver lobes. The adequacy of FNB samples for focal liver lesions located in the left and right lobes was 100% and 81.2%, respectively, and the difference was statistically significant (p = 0.001). Technical success was 100% for both liver lobes. The overall sensitivity and specificity were 95% and 100%, respectively. EUS-FNB is effective in making an accurate diagnosis with an excellent safety profile for focal liver lesions located in both liver lobes.
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页数:10
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