Reconstructive Surgery of the Head and Neck in Organ Transplant Recipients: A Case Report and a Review of the Literature

被引:0
作者
Rampi, Andrea [1 ]
Comini, Lara Valentina [2 ]
Galli, Andrea [3 ,4 ]
Howardson, Bright Oworae [3 ,4 ]
Tettamanti, Alberto [3 ,4 ]
Luparello, Paolo [2 ]
Redaelli, Gabriele [1 ]
Di Santo, Davide [2 ]
Bondi, Stefano [2 ]
机构
[1] Sondrio Hosp, Otorhinolaryngol Unit, ASST Valtellina & Alto Lario, I-23100 Sondrio, Italy
[2] FPO IRCCS, Candiolo Canc Inst, Otorhinolaryngol Head & Neck Surg, I-10060 Turin, Italy
[3] IRCCS San Raffaele Sci Inst, Div Head & Neck Dept, Otorhinolaryngol Unit, I-20132 Milan, Italy
[4] Univ Vita Salute San Raffaele, Sch Med, I-20132 Milan, Italy
关键词
head and neck surgery; solid organ recipients; wound healing; immunosuppressive agents; reconstructive flaps; WOUND-HEALING COMPLICATIONS; KIDNEY-TRANSPLANTATION; LIVER-TRANSPLANTATION; CANCER INCIDENCE; RISK; IMMUNOSUPPRESSION; TACROLIMUS; COHORT;
D O I
10.3390/jcm13164790
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The number of solid organ transplant recipients (SOTRs) is growing as a consequence of an increase in transplantations and longer survival; these patients, thus, frequently suffer various comorbidities and are subjected to the detrimental effects of immunosuppressive agents, which expose them to a higher risk of developing malignancies. These drugs also complicate the surgical treatment of neoplasms, as they can hinder wound healing, especially when associated with other unfavorable factors (e.g., previous radiotherapy, diabetes, etc.). We herein present our experience with a 74-year-old SOTR who underwent a radical extended parotidectomy and reconstruction with a submental island flap for a persistent cutaneous squamous carcinoma after radiotherapy; his complicated clinical course was characterized by incredibly slow wound healing. The current literature was reviewed to provide a succinct overview of the main difficulties of head and neck surgery in SOTRs. In particular, the immunosuppressive regimen can be tapered considering the individual risk and other elements should be carefully assessed, possibly prior to surgery, to prevent cumulative harm. New developments, including intraoperative monitoring of flap vascularization through indocyanine green fluorescence video-angiography and the prophylactic application of negative pressure wound therapy, when feasible, may be particularly beneficial for high-risk patients.
引用
收藏
页数:11
相关论文
共 50 条
  • [41] Renal aspergillosis in a liver transplant patient: A case report and review of literature
    Brigita Smolovic
    Batric Vukcevic
    Damir Muhovic
    Marina Ratkovic
    World Journal of Clinical Cases, 2018, (16) : 1155 - 1159
  • [42] Cryptococcal panniculitis in a renal transplant recipient: case report and review of literature
    Kothiwala, Sunil K.
    Prajapat, Mahesh
    Kuldeep, Chhitar Mal
    Jindal, Arpita
    JOURNAL OF DERMATOLOGICAL CASE REPORTS, 2015, 9 (03): : 76 - 80
  • [43] ANAL CANCER IN A RENAL TRANSPLANT RECIPIENT: A CASE REPORT AND LITERATURE REVIEW
    Mokos, Mislav
    Coric, Marijana
    Silovski, Hrvoje
    Basic-Jukic, Nikolina
    ACTA CLINICA CROATICA, 2023, 62 (03) : 556 - 560
  • [44] Emergence of letermovir resistance in solid organ transplant recipients with ganciclovir resistant cytomegalovirus infection: A case series and review of the literature
    Hofmann, Eveline
    Sidler, Daniel
    Dahdal, Suzan
    Bittel, Pascal
    Suter-Riniker, Franziska
    Manuel, Oriol
    Walti, Laura N.
    Hirzel, Cedric
    TRANSPLANT INFECTIOUS DISEASE, 2021, 23 (03)
  • [45] BK virus-associated nephropathy in a lung transplant patient: case report and literature review
    Crowhurst, Thomas
    Nolan, James
    Faull, Randall
    Holmes, Mark
    Holmes-Liew, Chien-Li
    BMC INFECTIOUS DISEASES, 2020, 20 (01)
  • [46] Renal aspergillosis in a liver transplant patient: A case report and review of literature
    Smolovic, Brigita
    Vukcevic, Batric
    Muhovic, Damir
    Ratkovic, Marina
    WORLD JOURNAL OF CLINICAL CASES, 2018, 6 (16) : 1155 - 1159
  • [47] The outcome of pregnancy in a kidney transplant patient: a case report and review of the literature
    Glisic, Andreja
    Divac, Nevena
    Dugalic, Miroslava Gojnic
    Kotlica, Biljana Kastratovic
    Vavic, Neven
    Cerovac, Natasa
    Prostran, Milica
    VOJNOSANITETSKI PREGLED, 2017, 74 (08) : 778 - 781
  • [48] Validity of patient skin cancer report among organ transplant recipients
    Dybbro, Eric
    Mihalis, Eva
    Hirose, Ryutaro
    Arron, Sarah T.
    CLINICAL TRANSPLANTATION, 2012, 26 (02) : E132 - E136
  • [49] Combined liver-kidney transplant for the management of methylmalonic aciduria: A case report and review of the literature
    Mc Guire, Peter J.
    Lim-Melia, Elizabeth
    Diaz, George A.
    Raymond, Kimiyo
    Larkin, Alexandra
    Wasserstein, Melissa P.
    Sansaricq, Claude
    MOLECULAR GENETICS AND METABOLISM, 2008, 93 (01) : 22 - 29
  • [50] Free tissue transfer for head and neck reconstruction in solid organ transplant patients
    Miller, Matthew W.
    Dean, Nichole R.
    Cannady, Steven B.
    Rosenthal, Eben L.
    Wax, Mark K.
    HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2012, 34 (08): : 1143 - 1146